41175-07-9Relevant academic research and scientific papers
Regioselective construction of 1,3-diaryl tetrahydroindazolones: Via the three-component reaction of 1,3-cyclohexanediones, β-nitrostyrenes and arylhydrazines
Wang, Ting,Qing, Xushun,Dai, Chenlu,Su, Zhenjie,Wang, Cunde
, p. 2456 - 2463 (2018/04/12)
1,5,6,7-Tetrahydro-4H-indazol-4-one derivatives were successfully synthesized using a one-pot three-component system that combines substituted β-nitrostyrenes, 1,3-cyclohexanediones and phenylhydrazines. This reaction involves a highly efficient domino sequence consisting of the aza-Michael reaction, intramolecular O-nucleophilic addition, nucleophilic addition, and ring opening of furan as the key unit steps. Notably, the highly regioselective construction of the tetrahydro-4H-indazolone moiety and the introduction of functionalized aromatic rings were achieved.
Synthetic method of 1,3-diaryl-1,5,6,7-tetrahydro-indazole derivant
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Paragraph 0027; 0028; 0029; 0030; 0051 0053; 0055; 0056, (2018/07/28)
The invention discloses a synthetic method of a 1,3-diaryl-1,5,6,7-tetrahydro-indazole derivant, and relates to the technical field of synthesis of indazole derivants. The synthetic method comprises the following steps: performing reaction on substituted 1,3-cyclohexanedione, substituted beta-nitryl aryl ethylene and substituted phenyl hydrazine by using triethylenediamine as a catalyst in presence of a solvent; performing steaming removal on residual solvents under reduced pressure after reaction is carried out and then adding water so as to obtain an organic phase; sequentially washing the organic phase with water and a saturated saline solution; then performing drying to obtain a crude product; performing column chromatography separation on the crude product to obtain the 1,3-diaryl-1,5,6,7-tetrahydro-indazole derivant. The synthetic method disclosed by the invention is high in yield and has easily-available raw materials; particularly, a substrate hydrazine participates in reactionso as to have highly area selectivity; a product is single, and post-treatment is concise. In addition, according to the method disclosed by the invention, using of a precious metal catalyst and thelike is not needed.
4,5,6,7-tetrahydro-3-aryl-indazoles and their use as herbicides
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, (2008/06/13)
The invention relates to novel herbicidal compounds of the formula I or I' STR1 in which X is an oxygen or sulfur atom, R1 is H, C1 -C6 -alkyl, C2 -C6 -alkenyl, C2 -C6 -alkynyl,
