69629-50-1

Upstream product

• 66049-39-6 3-oxo-1-cyclohexen-1-yl benzoate 
• 504-02-9 1,3-cylohexanedione 
• 288-88-0 1,2,4-Triazole 
• 98-88-4 benzoyl chloride 
• 201230-82-2 carbon monoxide 
• 98-80-6 phenylboronic acid 

Downstream Products

• 96546-38-2 3-phenyl-1,5,6,7-tetrahydro-4H-indazol-4-one 
• 79482-26-1 2-benzoyl-3-chloro-2-cyclohexen-1-one 
• 41175-07-9 1,3-diphenyl-1,5,6,7-tetrahydro-4H-indazol-4-one 
• 1575-25-3 1,3-diphenyl-1H-indazole 
• 96546-43-9 1,3-Diphenyl-4,5,6,7-tetrahydro-1H-indazol-4-ol 
• 13097-01-3 3-phenyl-1H-indazole 
• 63411-81-4 benzoyl-resorcinol 
• 102626-23-3 2,4-dichlorobenzene-1,3,5-tricarbaldehyde 
• 65-85-0 benzoic acid 
• 79482-30-7 3,8-dioxo-1-phenyl-5,6,7,8-tetrahydro-3H-2-benzopyran 
• 79482-22-7 2-benzoyl-3-methyl-2-cyclohexenone 
• 344266-54-2 2-benzoyl-3-(di-tert-butyloxycarbonyl)methylcyclohex-2-enone 
• 170457-06-4 3,5-diphenyl-4-hydroxy-4,5,6,7-tetrahydroindazole 
• 96546-42-8 4-hydroxy-4,5,6,7-tetrahydro-3-phenylindazole 

Relevant academic research and scientific papers

Effective synthesis of novel dihydrobenzisoxazoles bearing the 2-aminothiazole moiety and evaluation of the antiproliferative activity of their acylated derivatives

An effective method for the synthesis of 8-aryl-4,5-dihydrothiazolo[4′,5′:3,4]benzo[1,2-c]isoxazol-2-amines was developed. This method includes the α-keto bromination of 3-aryl-6,7-dihydrobenzo[c]isoxazol-4(5H)-ones followed by the condensation of the obt

Pd-catalyzed carbonylation for the construction of tertiary and quaternary carbon centers with sp3 carbon partners

The first examples of a Pd-catalyzed carbonylation of aryl boronic acids with sp3 carbon partners are presented. Various boronic acids were shown to react with 1,3-diesters and 1,3-diketones to afford structurally unique carbonyl compounds. By

NEW AMINOPYRAZOLOQUINAZOLINES

The present invention encompasses compounds of general formula (I) wherein the groups R1 to R3 and X are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferatio

AMINOPYRAZOLOQUINAZOLINES

Compounds of general formula (I) wherein the groups R1 to R3 and X are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, pharmaceutical preparations whi

SmCl3-catalyzed C-acylation of 1,3-dicarbonyl compounds and malononitrile

(Chemical Equation Presented) A recyclable, convenient, and efficient catalytic system for C-acylation of 1,3-dicarbonyl compounds and malononitrile with acid chlorides has been developed, giving moderate to excellent yields under mild conditions. This is the first catalytic example of such reactions. In addition, by applying this protocol as the key step, 3,5-disubstituted-1H- pyrazole-4-carboxylate can easily be synthesized in high yields in a one-pot procedure.

Method for acylating cyclic compounds

The method of this invention prepares acylated cyclic compounds by contacting phenyl esters as acylating agents with cyclic compounds in the presence of a cyanide or fluoride catalyst.

Process for the preparation of acylated cyclic 1,3-dicarbonyl compounds

A process for preparing a compound of Formula (I); where Q completes an optionally substituted 5-or 6-member saturated carbocyclic ring and R is optionally substituted phenyl or optionally substituted C3-C6 cycloalkyl which comprises the rearrangement of a compound of Formula (II); where Q and R are as defined in relation to Formula (I) in a polar aprotic, dipolar aprotic or aromatic hydrocarbon solvent in the presence of a moderate base and an azole.

SAR studies of 2-o-substituted-benzoyl- and 2-alkanoyl-cyclohexane-1,3-diones as inhibitors of 4-hydroxyphenylpyruvate dioxygenase

Inhibition studies of 4-hydroxyphenylpyruvate dioxygenase (HPPD) with various synthesized 2-o-substituted-benzoyl- and 2-alkanoyl-cyclohexane-1,3-diones suggest that the presence of a strongly electronegative group at the ortho position and the conformati

Synthesis and Photocyclization of 2-Aroyl-3-methylcyclohex-2-enones

Preparation and photocyclization of a number of 2-aroyl-3-methylcyclohex-2-enones have been investigated.Irradiation of these systems resulted in a photo-enolization followed by a pericyclic reaction to give 3,4-dihydroanthracen-1(2H)-ones.Keywords - prep