412015-27-1Relevant academic research and scientific papers
Synthesis, in vitro characterization, and radiolabeling of N,N-dimethyl-2-(2′-amino-4′-substituted-phenylthio)benzylamines: Potential candidates as selective serotonin transporter radioligands
Jarkas, Nachwa,McConathy, Jonathan,Voll, Ronald J.,Goodman, Mark M.
, p. 4254 - 4265 (2007/10/03)
A series of N,N-dimethylated and N-monomethylated analogues of N,N-dimethyl-2-(2′-amino-4′-iodophenylthio)benzylamine substituted at the 4′-phenyl position have been prepared and evaluated in vitro for serotonin transporter (SERT) selectivity. Several der
Carbon-11 labelling of MADAM in two different positions: a highly selective PET radioligand for the serotonin transporter
Tarkiainen, Jari,Vercouillie, Johnny,Emond, Patrick,Sandell, Johan,Hiltunen, Jukka,Frangin, Yves,Guilloteau, Denis,Halldin, Christer
, p. 1013 - 1024 (2007/10/03)
Imaging by scintigraphy the serotonin transporter (5-HTT) in the living human brain would be of great value in research on the pathophysiology and treatment of neuropsychiatric disorders such as depression. For that reason, and in order to obtain a select
