41212-91-3

Basic information

• Product Name: 7-chloro-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one benzylidenehydrazone
• CAS NO: 41212-91-3
• Molecular Weight: 372.857
• Mol File: 41212-91-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 7-chloro-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one benzylidenehydrazone(CAS DataBase Reference)
• NIST Chemistry Reference: 7-chloro-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one benzylidenehydrazone(41212-91-3)
• EPA Substance Registry System: 7-chloro-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one benzylidenehydrazone(41212-91-3)

Safety Data

• Hazardous Substances Data: 41212-91-3(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 18091-89-9 7-chloro-2-hydrazino-5-phenyl-3H-1,4-benzodiazepine 
• 719-59-5 5-chloro-2-aminobenzophenone 

Downstream Products

• 28910-95-4 8-chloro-1,6-diphenyl-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepine 

Relevant articles and documents

Electrochemical synthesis of 1,2,4-triazole-fused heterocycles

A reagent-free intramolecular dehydrogenative C-N cross-coupling reaction has been developed under mild electrolytic conditions. In this atom- and step-economical one-pot process, valuable 1,2,4-triazolo[4,3-a]pyridines and related heterocyclic compounds could be synthesized efficiently from commercially available aliphatic or (hetero)aromatic aldehydes and 2-hydrazinopyridines. Various functional groups are compatible with this metal- and oxidant-free protocol which can be carried out on a gram scale easily. This novel method was applied to the synthesis of one of the top-selling drugs Xanax and late stage functionalization for generating chemical diversity in biologically relevant lead molecules.