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41223-92-1

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41223-92-1 Usage

General Description

1H-Tetrazole-1-acetyl Chloride, also known as Acetyl Tetrazole Chloride, is a chemical compound often used in the field of organic synthesis. It is a white crystalline powder, and due to its reactive nature, it must be carefully handled and stored. This substance is highly corrosive and has a strong chemical odor. As a result, it may cause irritation to the skin and eyes. It serves as a vital reagent in various chemical reactions, particularly in the manufacturing processes for pharmaceuticals and high-performance polymers. Its molecular formula is C3H3ClN4.

Check Digit Verification of cas no

The CAS Registry Mumber 41223-92-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,1,2,2 and 3 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 41223-92:
(7*4)+(6*1)+(5*2)+(4*2)+(3*3)+(2*9)+(1*2)=81
81 % 10 = 1
So 41223-92-1 is a valid CAS Registry Number.

41223-92-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(tetrazol-1-yl)acetic acid chloride

1.2 Other means of identification

Product number -
Other names (1H-tetrazol-1-yl)acetyl chloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:41223-92-1 SDS

41223-92-1Relevant articles and documents

Identification of indole inhibitors of human hematopoietic prostaglandin D2 synthase (hH-PGDS)

Edfeldt, Fredrik,Even?s, Johan,Lepist?, Matti,Ward, Alison,Petersen, Jens,Wissler, Lisa,Rohman, Mattias,Sivars, Ulf,Svensson, Karin,Perry, Matthew,Feierberg, Isabella,Zhou, Xiao-Hong,Hansson, Thomas,Narjes, Frank

, p. 2496 - 2500 (2015/06/02)

Abstract Human H-PGDS has shown promise as a potential target for anti-allergic and anti-inflammatory drugs. Here we describe the discovery of a novel class of indole inhibitors, identified through focused screening of 42,000 compounds and evaluated using a series of hit validation assays that included fluorescence polarization binding, 1D NMR, ITC and chromogenic enzymatic assays. Compounds with low nanomolar potency, favorable physico-chemical properties and inhibitory activity in human mast cells have been identified. In addition, our studies suggest that the active site of hH-PGDS can accommodate larger structural diversity than previously thought, such as the introduction of polar groups in the inner part of the binding pocket.

studies on anti-helicobacter pylori agents. Part 2: New cephem derivatives

Yoshida, Yoshiki,Matsuda, Keiji,Sasaki, Hiroshi,Matsumoto, Yoshimi,Matsumoto, Satoru,Tawara, Shuichi,Takasugi, Hisashi

, p. 2317 - 2335 (2007/10/03)

The synthesis and optimization of the anti-Helicobacter pylori activity of a novel series of cephem derivatives are described. Introduction of thio-heterocyclic groups containing N- and S-atoms to the 3-position and phenyl or thienyl acetamido groups to the 7-position of the cephem nucleus dramatically improved the activity. From this series of derivatives, compound 13i was found to have extremely potent in vitro anti-H. pylori activity, superior therapeutic efficacy compared to AMPC and CAM, no cross-resistance between CAM or MNZ and low potential for causing diarrhea due to instability to β-lactamase. Copyright (C) 2000 Elsevier Science Ltd.

1-Oxacephalosporins: Enhancement of β-Lactam Reactivity and Antibacterial Activity

Murakami, Kazuhisa,Takasuka, Mamoru,Motokawa, Kiyoshi,Yoshida, Tadashi

, p. 88 - 93 (2007/10/02)

The effect of replacement of sulfur in the cephem nucleus by oxygen upon the β-lactamase stability, infrared carbonyl frequency of the β-lactam ring, and antibacterial activity was investigated.The replacement reduced the stability of β-lactam compounds t

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