412284-09-4

Upstream product

• 107-87-9 2-Pentanone 
• 35292-54-7 N-methyl-N-(p-methoxyphenyl)hydrazine 
• 17591-06-9 5-methoxy-1,2-dimethyl-1H-indole 
• 74-85-1 ethene 
• 17473-78-8 N’-(4-methoxyphenyl)acetohydrazide 
• 3471-32-7 4-Methoxyphenylhydrazine 
• 54653-29-1 (Z)-2-bromo-2-pentene 
• 1450812-53-9 N'-(4-methoxyphenyl)-N'-methylacetohydrazide 
• 854657-98-0 2,3-dibromo-2-methyl-valeric acid 
• 16957-70-3 2-methylpent-2-enoic acid 

Relevant academic research and scientific papers

Formation of enehydrazine intermediates through coupling of phenylhydrazines with vinyl halides: Entry into the Fischer indole synthesis

Cut to the chase: Direct formation of an enehydrazine, an intermediate in the classic Fischer indole synthesis, solves the regioselectivity problem associated with indolization. This approach not only achieves selective synthesis of indoles through proper selection of the vinyl halide, but also leads to quick construction of desoxyeseroline and esermethole, as well as the key structural motif in the Akuammiline alkaloid vincorine. Copyright

Platinum(II)-catalyzed intermolecular hydroarylation of unactivated alkenes with indoles

Ethylene, α-olefins, and vinyl arenes undergo platinum-catalyzed hydroarylation with substituted indoles in moderate to good yield. The Royal Society of Chemistry 2006.