412357-32-5

Basic information

• Product Name: tert-butyl 4-(1,3-dioxoisoindolin-2-yl)piperidine-1-carboxylate
• Synonyms: tert-butyl 4-(1,3-dioxoisoindolin-2-yl)piperidine-1-carboxylate
• CAS NO: 412357-32-5
• Molecular Formula: C18H22N2O4
• Molecular Weight: 330.37828
• Mol File: 412357-32-5.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: tert-butyl 4-(1,3-dioxoisoindolin-2-yl)piperidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 4-(1,3-dioxoisoindolin-2-yl)piperidine-1-carboxylate(412357-32-5)
• EPA Substance Registry System: tert-butyl 4-(1,3-dioxoisoindolin-2-yl)piperidine-1-carboxylate(412357-32-5)

Safety Data

• Hazardous Substances Data: 412357-32-5(Hazardous Substances Data)

Usage

General Description

Tert-butyl 4-(1,3-dioxoisoindolin-2-yl)piperidine-1-carboxylate, also known as Boc-L-Pro-isoindoline-2-carboxylic acid, is a chemical compound commonly used in organic synthesis. It is a derivative of the amino acid proline and contains a piperidine and isoindoline ring. The tert-butyl group at the N-terminal of the compound serves as a protecting group, making it useful in peptide synthesis. This chemical is often utilized in the pharmaceutical industry for the production of peptides and small molecules with potential drug properties. It is also a key building block for the preparation of complex organic compounds and can be used as a reagent in various chemical reactions. Additionally, its structural features make it a valuable tool in medicinal chemistry and drug discovery.

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Relevant articles and documents

HYDRAZINE COMPOUND AS BLOOD COAGULATION FACTOR Xa INHIBITOR

Provided is a compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein X is selected from a 3-9 membered carbon ring or its phenyl ring, and a 4-10 membered heterocyclic ring or its benzo ring; Y and Z are independently selected from 4-9 membered saturated heterocyclic rings respectively; RI-3 are independently selected from H, F, Cl, Br, I, CN, OH, SH,NH2, CHO, COOH respectively, or selected from C1-10 alkyls or heteroalkyls optionally substituted by R01, C3-10 alkyls ring hydrocarbon groups or heterocyclic hydrocarbon groups, C1-10 alkyls or heteroalkyls substituted by C3-10 ring hydrocarbon groups or heterocyclic hydrocarbon group. The compound can be used as an anticoagulant for treating and preventing thrombotic disorders, and can meet the real needs of selectivity and a potent inhibitor for coagulation Xa.

AMINE SUBSTITUTED PIPERIDINE MELANOCORTIN RECEPTOR-SPECIFIC COMPOUNDS

A compound of the formula I, where R1, R2a, R2b, R3, L1, L2, Q, J, X, m and n are as defined, or an enantiomer, stereoisomer or diastereoisomer thereof, or a pharmaceutically acceptable salt thereof, and the use thereof in the treatment of diseases, syndromes and conditions.

NITROGENOUS FIVE-MEMBERED RING COMPOUNDS

The present invention is to provide an aliphatic nitrogen-containing 5-membered ring compound represented by the formula [I] : wherein symbols in the formula have the following meanings;A: -CH2- or -S-,B: CH or N,R1: H, a lower alkyl group, etc.,X: a single bonding arm, -CO-, -Alk-CO-, -COCH2-, -Alk-O-, -O-CH2-, -SO2-, -S-, -COO-, -CON(R3)-, -Alk-CON(R3)-, -CON(R3)CH2-, -NHCH2-, etc.,R3: hydrogen atom or a lower alkyl group,Alk: a lower alkylene group, andR2: (1) a cyclic group which may be substituted, (2) a substituted amino group, etc., provided that when X is -CO-, then B is N, or a pharmaceutically acceptable salt thereof.