41264-56-6Relevant academic research and scientific papers
Hit-to-Lead studies: The discovery of potent adamantane amide P2X 7 receptor antagonists
Baxter, Andrew,Bent, Janice,Bowers, Keith,Braddock, Martin,Brough, Steve,Fagura, Malbinder,Lawson, Mandy,McInally, Tom,Mortimore, Mike,Robertson, Mark,Weaver, Richard,Webborn, Peter
, p. 4047 - 4050 (2007/10/03)
A Hit-to-Lead optimisation programme was carried out on the adamantane high throughput screening hit 1 resulting in the discovery of a number of potent P2X7 antagonists.
SYNTHESIS AND TRANSFORMATIONS OF N-ADAMANTYL-SUBSTITUTED OXAZIRIDINES
Isaev, S. D.,Novoselov, E. F.,Yurchenko, A. G.
, p. 103 - 108 (2007/10/02)
N-Adamantyl-substituted oxaziridines were obtained by the oxidation of the Schiff bases synthesized from adamantyl-containing amines with peroxyacetic acid.The thermal rearrangement and fragmentation under the influence of Fe(II) ions, leading to nitrones
