41280-65-3

Usage

Uses

Used in Pharmaceutical and Agricultural Chemical Industries:
2-Bromo-4-t-butylanisole is utilized as a building block in the synthesis of various pharmaceuticals and agricultural chemicals. Its role in these industries is crucial for creating new compounds with potential therapeutic or pesticidal properties.
Used in the Food Industry:
In the food industry, 2-Bromo-4-t-butylanisole is employed as a flavoring agent. It contributes to the development of unique tastes and scents in food products, enhancing the overall sensory experience for consumers.

Upstream product

• 2198-66-5 2-bromo-4-tert-butylphenol 
• 77-78-1 dimethyl sulfate 
• 5396-38-3 1-(tert-butyl)-4-methoxybenzene 
• 98-54-4 para-tert-butylphenol 
• 74-88-4 methyl iodide 
• 1609573-33-2 8-bromo-3,6-di-tert-butyl-3,4-dihydro-2H-benzo[e][1,3]oxazine 

Downstream Products

• 132098-47-6 1,6-bis(5-tert-butyl-2-methoxyphenyl)hexane 
• 108656-63-9 1,3-bis(5-tert-butyl-2-methoxyphenyl)propane 
• 132098-48-7 1,8-bis(5-tert-butyl-2-methoxyphenyl)octane 
• 169478-48-2 1,7-bis(5-tert-butyl-2-methoxyphenyl)heptane 
• 132098-49-8 1,10-bis(5-tert-butyl-2-methoxyphenyl)decane 
• 182007-02-9 1,1-Bis-(5-tert-butyl-2-methoxy-phenyl)-ethanol 
• 182007-01-8 bis(5-tert-butyl-2-methoxyphenyl)methanol 
• 182007-03-0 Bis-(5-tert-butyl-2-methoxy-phenyl)-phenyl-methanol 
• 98085-84-8 2,2'-Dimethoxy-5,5'-di-tert-butyldiphenylmethane 
• 171002-41-8 2,9-bis(5-tert-butyl-2-methoxyphenyl)-1,10-phenanthroline 
• 1114569-65-1 C₂₂H₃₁NO₂ 
• 1158910-45-2 2-(5-(tert-butyl)-2-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 1096677-12-1 2-benzyl-4-(5-tert-butyl-2-methoxyphenyl)-5,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-4-ol 
• 1335244-28-4 C₃₄H₃₈O₂ 

Relevant academic research and scientific papers

Selective metalation of phenol-type proligands for preparative organometallic chemistry

The selective C-metalation of phenol ester derived proligands is a readily applicable addition to state-of-the-art protocols toward cyclometalated structures, in particular of the base metals. The approach is demonstrated by the ortho-nickelation of a 1,10-phenanthroline based strong-field ligand platform that is a sought-after motif in the field of base-metal photochemistry.

Preparation of a novel bromine complex and its application in organic synthesis

Although molecular bromine (Br2) is a useful brominating reagent, it is not easy to handle. Herein, we describe the preparation of a novel air-stable bromine complex prepared from 1,3-dimethyl-2-imidazolidinone (DMI) and Br2, which was identified to be (DMI)2HBr3 by spectral and X-ray techniques. This complex was then used to brominate olefins, carbonyl compounds, and aromatics, as well as in the Hofmann rearrangement. Yields of reaction products using this complex were almost the same or superior to those using other bromine alternatives.

Atom-economical brominations with tribromide complexes in the presence of oxidants

Bromination is an important transformation in organic synthesis, and novel efficient bromination techniques are still required. Herein, we demonstrate atom-economical brominations using (DMI)2HBr3, a novel tribromide complex, with oxidants such as DMSO and Oxone. Using this system, olefinic and aromatic brominations, as well as selective α-monobrominations of ketones proceeded well to afford the desired bromides in good yields. Importantly, in these reactions all of the bromine atoms in this complex are used to brominate.

Development of Chiral C2-Symmetric N-Heterocyclic Carbene Rh(I) Catalysts through Control of Their Steric Properties

Chiral square-planar Rh(I) complexes based on new C2-symmetric NHC ligands have been synthesized selectively in a few steps as single diastereoisomers. These chiral precatalysts were applied to the asymmetric transfer hydrogenation of 1-phenylp

NOVEL LIGAND COMPOUND AND TRANSITION METAL COMPOUND COMPRISING THE SAME

The present invention relates to a novel ligand compound and a transition metal compound including the same. The transition metal compound with a novel structure according to the present invention can be used as a polymerization reaction catalyst when an olefin polymer is manufactured. The novel ligand compound has a structure in which two biphenyl-2-ols are connected to pyridine by methylene, respectively. An oxygen atom of biphenyl-2-ol is covalently bonded to the transition metal and a nitrogen atom of pyridine is coordinately bonded to the transition metal.COPYRIGHT KIPO 2018

Substituted Pyrrolidines and Methods of Use

The invention discloses compounds of Formula (I) wherein R1, R2, R2A, R3, R3A, R4, and R5 are as defined herein. The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions comprising the same, and methods of treating cystic fibrosis by administering a compound of the invention.

UREA DERIVATIVES USEFUL AS KINASE INHIBITORS

There are provided compounds of formula I, wherein R1, R1A, R1C to R1E, Ra, Rb, X1, E and G have meanings given in the description, which compounds have antiinflammatory activity (e.g. through inhibition of one or more of members of: the family of p38 mitogen-activated protein kinase enzymes; Syk kinase; and members of the Src family of tyrosine kinases) and have use in therapy, including in pharmaceutical combinations, especially in the treatment of inflammatory diseases, including inflammatory diseases of the lung, eye and intestines.

Synthesis of dilactone bridged terphenyls with crankshaft architectures

Three highly fluorescent dilactone bridged terphenyls with crankshaft architectures have been synthesized. This general class of compounds is relatively unexplored. These compounds have been characterized by fluorescence and UV-vis spectroscopy. For all three compounds, a direct correlation between the rigidity of the terphenyl system and the strength of absorption and emission of light has been observed. Preliminary studies have indicated that compounds with this architecture have the potential to be useful as pH-driven molecular switches and/or sensors with instant fluorescence attenuation at high pH values.

HETEROARYL DERIVATIVES AND USES THEREOF

The present invention relates to antimalarial compounds and their use against protozoa of the genus Plasmodium, including drug-resistant Plasmodia strains. This invention further relates to compositions containing such compounds and a process for making the compounds.

Aryl Derivatives And Uses Thereof

The present invention relates to antimalarial compounds and their use against protozoa of the genus Plasmodium, including drug-resistant Plasmodia strains. This invention further relates to compositions containing such compounds and a process for making the compounds.