41288-94-2Relevant academic research and scientific papers
The Reaction of Some Halogenated Pyridine Thioethers and Sulphones with Carbon Disulphide
Dunn, A. D.,Norrie, R.
, p. 269 - 272 (1993)
Dithiocarboxylation of some halogenated pyridine sulphones with carbon disulphide and sodium hydride leads to the formation of thiomethyl derivatives via Smiles rearrangement of the initially produced dianion, fragmentation and subsequent methylation.In one instance the pyridino-1,4-dithiine 7 was obtained.The thioether 2d was also converted into a thiomethyl derivative when subjected to the same reaction sequence.
PHD INHIBITOR COMPOUNDS, COMPOSITIONS, AND THEIR USE
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Paragraph 0474-0475, (2021/09/26)
The present invention provides, in part, novel small molecule inhibitors of PHD, having a structure according to Formula (A), and sub-formulas thereof: or a pharmaceutically acceptable salt thereof. The compounds provided herein can be useful for treatmen
PHD INHIBITOR COMPOUNDS, COMPOSITIONS, AND USE
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Paragraph 0425-0426, (2021/09/26)
The present invention provides, in part, novel small molecule inhibitors of PHD, having a structure according to Formula (A), and sub-formulas thereof: or a pharmaceutically acceptable salt thereof. The compounds provided herein can be useful for treatment of diseases including heart ( e.g. ischemic heart disease, congestive heart failure, and valvular heart disease), lung (e.g., acute lung injury, pulmonary hypertension, pulmonary fibrosis, and chronic obstructive pulmonary disease), liver (e.g. acute liver failure and liver fibrosis and cirrhosis), and kidney (e.g. acute kidney injury and chronic kidney disease) disease.
SUCCINATE AND FUMARATE ACID ADDITION SALTS OF PIPERAZINE DERIVATIVES USEFUL AS GLYCOSIDASE INHIBITORS
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Page/Page column 30, (2020/03/15)
The invention relates to succinic acid addition salts or fumaric acid addition salts of piperazine derivatives of formula (I), as well as solid forms, such as polymorphic forms, thereof, which are useful as pharmaceutical ingredients and in particular as
LINEAR GLYCOSIDASE INHIBITORS
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Page/Page column 98, (2019/03/14)
Compounds of formula (I) wherein A, R, W, Q, L, n and m have the meaning according to the claims can be employed, inter alia, for the treatment of tauopathies and Alzheimer's disease.
New efficient access to thieno[3,2-b]pyridine derivatives via regioselective lithiation of 3-methylthiopyridine
Comoy, Corinne,Banaszak, Estelle,Fort, Yves
, p. 6036 - 6041 (2007/10/03)
The synthesis of thieno[3,2-b]pyridines was achieved using a three-step process allowing the construction of the thiophenic ring with 17-34% overall yields. The key step was the regioselective lithiation-bromination of the 3-methylthiopyridine induced by
Insecticidal N-substituted sulfoximines
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Page/Page column 10, (2010/02/14)
N-Substituted sulfoximines are effective at controlling insects.
