412947-53-6

Basic information

• Product Name: 2-ethynyl-4-(methoxycarbonyl)aniline
• Synonyms: 2-ethynyl-4-(methoxycarbonyl)aniline
• CAS NO: 412947-53-6
• Molecular Weight: 175.187
• Mol File: 412947-53-6.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: 2-ethynyl-4-(methoxycarbonyl)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ethynyl-4-(methoxycarbonyl)aniline(412947-53-6)
• EPA Substance Registry System: 2-ethynyl-4-(methoxycarbonyl)aniline(412947-53-6)

Safety Data

• Hazardous Substances Data: 412947-53-6(Hazardous Substances Data)

Upstream product

• 19718-49-1 4-amino-3-iodobenzoic acid methyl ester 
• 74-86-2 acetylene 
• 619-45-4 4-methoxycarbonyl aniline 
• 916486-08-3 4-methoxycarbonyl-2-(trimethylsilylethynyl)aniline 

Downstream Products

• 916486-09-4 4-amino-3-[(1-methylamino-pyrimidin-4-yl)-ethynyl]benzoic acid methyl ester 
• 1224955-46-7 C₁₈H₁₃F₃N₂O₃ 
• 1186610-45-6 2-ethynyl-4-(methoxycarbonyl)-N-(p-toluenesulfonyl)aniline 

Relevant articles and documents

Copper-Catalyzed Trifluoromethylation/Cyclization of Alkynes for Synthesis of Dioxodibenzothiazepines

A facile and efficient approach for the synthesis of the CF3-containing dioxodibenzothiazepines has been developed via copper-catalyzed trifluoromethylation/cyclization of alkynes utilizing a radical relay strategy. This method has demonstrated low cataly

INDOLINONE DERIVATIVES AS INHIBITORS OF MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE

The present disclosure relates to indolinone compounds, compositions, and methods for the inhibition of maternal embryonic leucine zipper kinase (MELK). The present disclosure further relates to indolinone compounds, compositions, and methods for the treatment or prevention of a cancer (for example, triple negative breast cancer).

[Cp*IrCl2]2 catalyzed formation of 2,2′-biindoles from 2-ethynylanilines

[Cp*IrCl2]2 catalyzes the cyclization of 2-ethynylanilines to 2,2′-biindoles via intramolecular hydroamination. A reaction pathway has been proposed on the basis of deuterium labeling experiments and computational studies.