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1-Isopropyl-2,5-dimethylbenzene is an organic compound with the molecular formula C??H??. It is a derivative of benzene, featuring an isopropyl group attached to the first carbon atom and two methyl groups attached to the second and fifth carbon atoms, respectively. This aromatic hydrocarbon is a colorless liquid with a distinctive odor and is insoluble in water but soluble in organic solvents. It is primarily used as a chemical intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other organic compounds. Due to its complex structure, 1-isopropyl-2,5-dimethylbenzene is not found naturally and is produced through chemical synthesis methods.

4132-72-3

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4132-72-3 Usage

Physical state

Colorless liquid

Odor

Strong

Natural occurrence

Found in essential oils of cumin and thyme

Uses

+ Flavoring agent in food and beverages
+ Fragrance in cosmetic and personal care products
+ Ingredient in pharmaceuticals and household cleaning products due to antiseptic and antimicrobial properties

Therapeutic effects

+ Reduces inflammation
+ Promotes wound healing

Safety concerns

+ Can be irritant to skin, eyes, and respiratory system
+ May cause allergic reactions in some individuals

Check Digit Verification of cas no

The CAS Registry Mumber 4132-72-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,1,3 and 2 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 4132-72:
(6*4)+(5*1)+(4*3)+(3*2)+(2*7)+(1*2)=63
63 % 10 = 3
So 4132-72-3 is a valid CAS Registry Number.
InChI:InChI=1/C11H16/c1-8(2)11-7-9(3)5-6-10(11)4/h5-8H,1-4H3

4132-72-3Relevant academic research and scientific papers

Isopropylation of xylenes catalyzed by ultrastable zeolite Y (USY) and some other solid acid catalysts

Patra, Chitta Ranjan,Kumar, Rajiv

, p. 216 - 224 (2007/10/03)

The isopropylation of all three xylene isomers was carried out over ultrastable zeolite Y (USY) catalyst to give corresponding dimethyl (1-methylethyl) benzenes, or in other words dimethyl cumenes (DMCs), using isopropanol as alkylating agent. The effect of reaction temperature, space velocity, substrate-to-alkylating-agent molar ratio, and time-on-stream on conversion of xylene isomers and selectivity to dimethyl cumene was studied. Isopropylation of xylenes over USY gives quite high (80 to 95%) DMC selectivity among the dimethyl cumenes, along with a 70-90% yield of DMCs in total products with respect to limiting reagents, i.e., isopropylating agents at relatively low reaction temperatures (423 ± 10 K) and at quite high xylene conversions (85-97% of theoretical maximum value). The solid acid catalysts zeolites H-Y, H-beta, H-mordenite, as well as silica-alumina and sulfated zirconia, were included for comparative studies in the isopropylation of m-xylene.

STEREOSELECTIVE COMPLEXATION OF PROCHIRAL ARENES. PART I. ASYMMETRIC INDUCTION MEDIATED BY AN ALPHA CHIRAL CENTER

Rosca, Sinziana,Orfanu, Cristina,Stan, Raluca,Rosca, Sorin I.

, p. 1225 - 1234 (2007/10/03)

Diastereoselective Cr(CO)3-complexation of 2,5-dimethylphenyl-alkyl-carbinols was studied. Depending on the structure of the asymmetric alpha carbon atom, a diastereomeric excess of 12-96 percent was obtained. A relative configuration R*S* of the resulted complexes is infered, indicating a preferential complexation from the same side with carbinolic hydroxyl group.

Kinetics and Regioselectivity of the Autoxidation of o-Substituted Isopropyl Aromatics

Heinze, Antje,Lauterbach, Gerlinde,Pritzkow, Wilhelm,Schmidt-Renner, Wolfgang,Voerckel, Volkmar,Zewegsuren, Nansadyn

, p. 439 - 446 (2007/10/02)

The relative chain propagation constants and the regioselectivities of the oxidations of o-cymene and 2-isopropyl-1,4-dimethylbenzene were determined by competitive oxidations of the hydrocarbons with cumene.As expected, the reactivity of the tertiary C-H bond of the isopropyl group is considerably decreased by o-methyl groups.Also in α-isopropylnaphthalene a considerable decrease in the reactivity of the tertiary C-H bond takes place.The decrease of the chain propagation constants effects a decrease of the oxidabilities of o-substituted isopropyl aromatics.In the case of the methyl isopropyl benzenes the increase of the chain termination constants by primary peroxy radicals must also be taken into consideration.This results in a decrease of the oxidabilities which can be observed even in p-cymene (in comparison with cumene).

Preparation, Pyrolysis, and Photolysis of Three Sterically Crowded Alkenes, 3,3,3',3',5,5,5',5'-Octamethyl-3,3',5,5'-tetrahydro-4,4'-bi(4H-pyrazolylidene) 2,2,4,4-Tetramethyl-3-(3,3,5,5-tetramethyl-3,5-dihydro-4H-pyrazol-4-ylidene)-thietane 1,1-Dioxide and 2,2,2',2',4,4,4',4'-Octameth...

Bushby, Richard J.,Mann, Stephen,Jesudason, Malini, V.

, p. 2457 - 2464 (2007/10/02)

Photolysis and pyrolysis of the title compounds involve a stepwise elimination of nitrogen and/or sulphur dioxide and reactions which can be interpreted in terms of a series of trimethylenemethane (TMM) biradical intermediates.However, the photosensitised photolysis of the bi(pyrazolylidene) (11) give products indicative of an elimination of both nitrogens and the generation of a tetramethylene-ethane (TME) biradical intermediate.New synthesis of a number of highly sterically crowded alkenes including 2,2,4,4-tetramethyl-3-(3,3,5,5-tetramethyl-3,4-dihydro-4H-pyrazol-4-ylidene)thietane 1,1-dioxide (12) and 2,2,2',2',4,4,4',4'-octamethyl-3,3'-bithietanylidene 1,1,1',1'-tetraoxide (13), are described.Flash vacuum pyrolysis (f.v.p) of 3,3,3',3',5,5,5',5'-octamethyl-3,3'-5,5'-tetrahydro-4,4'-bi(4H-pyrazolylidene) (11) at 400 deg C gives 3,3,5,5-tetramethyl-4-(2,2,3,3-tetramethylcyclopropylidene)-3,5-dihydro-4H-pyrazole (21), at ca. 400 deg C 1-isopropylidene-2,2,4,4,5,5-hexamethylspiropentane (22), and at ca. 580 deg C a ca. 5:1 mixture of 4-isopropyl-3-isopropylidene-2,5-dimethylhexa-1,4-diene (23) and 2-(2,3-dimethylbut-1-en-3-yl)-1-isopropyl-3,3-dimethylcyclopropene (27).Above 700 deg C a complex mixture of aromatic products and low molecular weight hydrocarbons is produced which includes ethane, ethylene, propene, isobutane, and isobutene, p-xylene, o-cumene and probably m-cumene, and 2,5-dimethylisopropylbenzene.F.v.p. of the dihydropyrazole sulphone (12) gives initially 2,2,4,4-tetramethyl-3-(2,2,3,3,-tetramethylcyclopropylidene)thietane 1,1-dioxide (41) and at higher temperatures similar mixtures to those obtained from the bipyrazolylidene (11).Similar results were also obtained for the f.v.p. of the bis-sulphone (13).Photolysis of the bipyrazolylidene (11) gave initially the dihydropyrazole (21) and then a 48:52 mixture of the spiro compound (22) and 2,2,2',2',3,3,3',3'-octamethylbicyclopropylidene (42).Photolysis of the dihydropyrazole sulphone (12) gave 2,2,4,4-tetramethyl-3-(2,2,3,3-tetramethylcyclopropylidene)thietane 1,1-dioxide (41).Benzophenone-sensitised photolysis of the bipyrazolylidene (11) gave 1,2-di-isopropylidene-3,3,4,4-tetramethylcyclobutane (32).

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