41341-50-8Relevant academic research and scientific papers
Synthesis of disaccharide nucleosides by the O-glycosylation of natural nucleosides with thioglycoside donors
Aoki, Shin,Fukumoto, Taketo,Itoh, Taiki,Kurihara, Masayuki,Saito, Shigeto,Komabiki, Shin-Ya
, p. 740 - 751 (2015)
Disaccharide nucleosides constitute an important group of naturally-occurring sugar derivatives. In this study, we report on the synthesis of disaccharide nucleosides by the direct O-glycosylation of nucleoside acceptors, such as adenosine, guanosine, thy
Stereoretentive palladium-catalyzed arylation, alkenylation, and alkynylation of 1-thiosugars and thiols using aminobiphenyl palladacycle precatalyst at room temperature
Bruneau, Alexandre,Roche, Maxime,Hamze, Abdallah,Brion, Jean-Daniel,Alami, Mouad,Messaoudi, Samir
, p. 8375 - 8379 (2015/06/02)
A general and efficient protocol for the palladium-catalyzed functionalization of mono- and polyglycosyl thiols by using the palladacycle precatalyst G3-XantPhos was developed. The C-S bond-forming reaction was achieved rapidly at room temperature with various functionalized (hetero)aryl-, alkenyl-, and alkynyl halides. The functional group tolerance on the electrophilic partner is typically high and anomer selectivities of thioglycosides are high in all cases studied. New sulfur nucleophiles such as thiophenols, alkythiols, and thioaminoacids (cysteine) were also successfully coupled to lead to the most general and practical method yet reported for the functionalization of thiols.
Thio-arylglycosides with various aglycon para-substituents: A probe for studying chemical glycosylation reactions
Li, Xiaoning,Huang, Lijun,Hu, Xiche,Huang, Xuefei
experimental part, p. 117 - 127 (2009/04/08)
Three series of thioglycosyl donors differing only in their respective aglycon substituents within each series have been prepared as representatives of typical glycosyl donors. The relative anomeric reactivities of these donors were quantified under compe
