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  • 41373-90-4 Structure
  • Basic information

    1. Product Name: 4-PHENYL-3,6-PYRIDAZINEDIOL
    2. Synonyms: 4-PHENYL-3,6-PYRIDAZINEDIOL;3(2H)-Pyridazinone, 6-hydroxy-4-phenyl-;4-phenylpyridazine-3,6-diol;4-Phenyl-1,2-dihydro-3,6-pyridazinedione
    3. CAS NO:41373-90-4
    4. Molecular Formula: C10H8N2O2
    5. Molecular Weight: 188.185
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 41373-90-4.mol
    9. Article Data: 8
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.28g/cm3
    6. Refractive Index: 1.588
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-PHENYL-3,6-PYRIDAZINEDIOL(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-PHENYL-3,6-PYRIDAZINEDIOL(41373-90-4)
    11. EPA Substance Registry System: 4-PHENYL-3,6-PYRIDAZINEDIOL(41373-90-4)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 41373-90-4(Hazardous Substances Data)

41373-90-4 Usage

Description

4-PHENYL-3,6-PYRIDAZINEDIOL, also known as KMD-3213, is a chemical compound belonging to the pyridazin-3(2H)-one family. It is a novel drug candidate with potential antitumor and anticancer properties. 4-PHENYL-3,6-PYRIDAZINEDIOL exhibits a high degree of selectivity towards cancer cells, making it a promising option for cancer treatment. It functions by inhibiting the activity of certain enzymes involved in cancer cell proliferation and survival. Moreover, it has demonstrated low toxicity in preclinical studies, suggesting a favorable safety profile for use in humans.

Uses

Used in Oncology:
4-PHENYL-3,6-PYRIDAZINEDIOL is used as an anticancer agent for its potential to selectively target and inhibit the growth of cancer cells. It is particularly effective in treating various types of cancer due to its ability to interfere with the enzymes that promote cell proliferation and survival in cancerous cells.
Used in Drug Development:
4-PHENYL-3,6-PYRIDAZINEDIOL is used as a drug candidate in the development of novel cancer therapies. Its high selectivity for cancer cells and low toxicity make it a valuable compound for further research and clinical trials to fully understand its therapeutic potential in cancer treatment.
Used in Pharmaceutical Research:
4-PHENYL-3,6-PYRIDAZINEDIOL is used as a subject of research in the pharmaceutical industry to explore its potential applications in cancer treatment. Further studies are needed to investigate its mechanism of action, efficacy, and safety in treating different types of cancer, as well as to develop optimal drug delivery systems for its administration.

Check Digit Verification of cas no

The CAS Registry Mumber 41373-90-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,1,3,7 and 3 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 41373-90:
(7*4)+(6*1)+(5*3)+(4*7)+(3*3)+(2*9)+(1*0)=104
104 % 10 = 4
So 41373-90-4 is a valid CAS Registry Number.
InChI:InChI=1/C10H8N2O2/c13-9-6-8(10(14)12-11-9)7-4-2-1-3-5-7/h1-6H,(H,11,13)(H,12,14)

41373-90-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-Phenyl-1,2-dihydro-3,6-pyridazinedione

1.2 Other means of identification

Product number -
Other names 4-phenyl-1,2-dihydro-pyridazine-3,6-dione

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:41373-90-4 SDS

41373-90-4Relevant articles and documents

Pyridazinone derivative and application thereof

-

Paragraph 0190-0195, (2020/11/23)

The invention provides a pyridazinone derivative and an application thereof, the pyridazinone derivative with the structure shown in the formula (I) provided by the invention has good activity as a thyroid hormone beta receptor agonist by selecting a specific modification group. The compound can be used for treating and/or preventing diseases caused by thyroid hormone regulation.

SUBSTITUTED IMIDAZO[1,2-B]PYRIDAZINES

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Paragraph 0584, (2013/08/28)

The invention relates to imidazo[1,2-b]pyridazines of general formula (I) a process for their manufacuture and their use for the treatment of benign and malignant neoplasia.

SUBSTITUTED HETEROCYCLIC COMPOUNDS AND METHODS OF USE

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Page/Page column 68, (2010/10/20)

The present invention relates to pyridines, pyrimidines and derivatives thereof, and pharmaceutically acceptable salts thereof. Also included is a method of treatment of inflammation, rheumatoid arthritis, Pagets disease, osteoporosis, multiple myeloma, uveititis, acute or chronic myelogenous leukemia, pancreatic beta cell destruction, osteoarthritis, rheumatoid spondylitis, gouty arthritis, inflammatory bowel disease, adult respiratory distress syndrome (ARDS), psoriasis, Crohn's disease, allergic rhinitis, ulcerative colitis, anaphylaxis, contact dermatitis, asthma, muscle degeneration, cachexia, Reiter's syndrome, type I diabetes, type II diabetes, bone resorption diseases, graft vs. host reaction, Alzheimer's disease, stroke, myocardial infarction, ischemia reperfusion injury, atherosclerosis, brain trauma, multiple sclerosis, cerebral malaria, sepsis, septic shock, toxic shock syndrome, fever, myalgias due to HIV-1, HIV-2, HIV-3, cytomegalovirus (CMV), influenza, adenovirus, the herpes viruses or herpes zoster infection in a mammal comprising administering an effective amount a compound as described above.

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