54248-86-1

Usage

Pharmacological activities

anti-inflammatory, analgesic, antimicrobial
Building block in the synthesis of novel drug candidates
Reference standard in analytical chemistry

Upstream product

• 41373-90-4 4-Phenyl-3,6-dioxo-1,2,3,6-tetrahydropyridazine 
• 16110-98-8 (Z)-2-phenylbut-2-enedioic acid 
• 591-50-4 iodobenzene 
• 869487-49-0 6-chloro-5-phenyl-3-pyridazinylhydrazine 
• 78-39-7 Triethyl orthoacetate 
• 41373-96-0 3,6-dichloro-4-phenyl-pyridazine 

Relevant academic research and scientific papers

Facile Synthesis of New [1,2,4]Triazolo[4,3-b]pyridazine

A number of new [1,2,4]triazolo[4,3-b]pyridazines were prepared by either cyclocondesation of substituted hydrazinopyridazines with orthoesters or oxidative cyclization of their hydrazone analogs in nitrobenzene as an oxidizing agent. A host of other new

TRIAZOLO-PYRIDAZINE COMPOUNDS AND DERIVATIVES THEREOF USEFUL IN THE TREATMENT OF NEUROPATHIC PAIN

The present invention is directed to a method of use of triazolo-pyridazine compounds in the treatment of neuropathic pain. The present invention is also directed to the use of triazolo-pyridazine compounds in the treatment of psychiatric and mood disorders such as, for example, schizophrenia, anxiety, depression, bipolar disorders, and panic, as well as in the treatment of pain, Parkinson’s disease, cognitive dysfunction, epilepsy, circadian rhythm and sleep disorders - such as shift-work induced sleep disorder and jet-lag, drug addiction, drug abuse, drug withdrawal and other diseases. The present invention is also directed to novel triazolo-pyridazine compounds that selectively bind to α2δ-1 subunit of Ca channels.