16110-98-8

Basic information

• Product Name: PHENYLMALEIC ACID
• Synonyms: 2-PHENYL-2-BUTENEDIOIC ACID;PHENYLMALEIC ACID;(Z)-2-Phenyl-2-butenedioic acid;2-Phenylmaleic acid;2-Butenedioic acid, 2-phenyl-, (2Z)-;2-Phenyl-2-butenedioic acid, (Z)-;L16395
• CAS NO: 16110-98-8
• Molecular Formula: C₁₀H₈O₄
• Molecular Weight: 192.17
• EINECS: 200-258-5
• Mol File: 16110-98-8.mol
• Article Data: 8

Chemical Properties

• Melting Point: 107-108°C
• Boiling Point: 347.8°Cat760mmHg
• Flash Point: 178.3°C
• Appearance: /
• Density: 1.377g/cm³
• Vapor Pressure: 1.98E-05mmHg at 25°C
• Refractive Index: 1.612
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 2.38±0.36(Predicted)
• BRN: 2259952
• CAS DataBase Reference: PHENYLMALEIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: PHENYLMALEIC ACID(16110-98-8)
• EPA Substance Registry System: PHENYLMALEIC ACID(16110-98-8)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36
• TSCA: Yes
• Hazardous Substances Data: 16110-98-8(Hazardous Substances Data)

Usage

General Description

Phenylmaleic acid is a chemical compound with the chemical formula C8H6O4. It is a white crystalline solid that is sparingly soluble in water. Phenylmaleic acid is primarily used as a starting material in the synthesis of various organic compounds, including pharmaceuticals and agrochemicals. It is also used as a building block in the production of polymers and resins. Phenylmaleic acid has applications in the manufacturing of adhesives, coatings, and sealants. It is important to handle phenylmaleic acid with care as it can cause irritation to the skin, eyes, and respiratory system and may be harmful if ingested or inhaled.

InChI:InChI=1/C10H8O4/c11-9(12)6-8(10(13)14)7-4-2-1-3-5-7/h1-6H,(H,11,12)(H,13,14)/b8-6+

Upstream product

• 591-50-4 iodobenzene 
• 110-17-8 (2E)-but-2-enedioic acid 
• 133710-07-3 (Z)-3-(tert-butylcarbamoyl)-2-phenylacrylic acid 
• 201230-82-2 carbon monoxide 
• 492-38-6 2-phenylacrylic acid 
• 536-74-3 phenylacetylene 
• 635-51-8 2-phenylsuccinic acid 
• 36122-35-7 2-phenylmaleic anhydride 
• 7732-18-5 water 
• 1603-79-8 phenylglyoxylic acid ethyl ester 
• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 67-56-1 methanol 
• 55815-01-5 2-methoxy-6-phenyl-1,4-benzoquinone 

Downstream Products

• 4808-48-4 2,3-diphenylmaleic anhydride 
• 104594-85-6 [2]naphthyl-phenyl-maleic acid-anhydride 
• 70982-94-4 3,5,6-triphenyl-(2H)-pyran-2-one 
• 41373-96-0 3,6-dichloro-4-phenyl-pyridazine 
• 869487-49-0 6-chloro-5-phenyl-3-pyridazinylhydrazine 
• 54248-83-8 6-chloro-7-phenyl-[1,2,4]triazolo[4,3-b]pyridazine 
• 54248-86-1 3-methyl-7-phenyl-[1,2,4]triazolo[4,3-b]pyridazine-6-ylchloride 
• 54248-88-3 3,7-diphenyl-[1,2,4]triazolo[4,3-b]pyridazine-6-ylchloride 

Relevant articles and documents

Facile Synthesis of New [1,2,4]Triazolo[4,3-b]pyridazine

A number of new [1,2,4]triazolo[4,3-b]pyridazines were prepared by either cyclocondesation of substituted hydrazinopyridazines with orthoesters or oxidative cyclization of their hydrazone analogs in nitrobenzene as an oxidizing agent. A host of other new

Synthesis of 1,2- and 1,3-dicarboxylic acids via Pd(II)-catalyzed carboxylation of aryl and vinyl C-H bonds

A Pd(II)-catalyzed reaction protocol for the direct carboxylation of benzoic and phenylacetic acid derivatives to form dicarboxylic acids has been developed. The reaction conditions are also applicable for the carboxylation of vinyl C-H bonds. The first C-H insertion Pd-aryl complex from carboxylic acids has been characterized by X-ray crystallography. Copyright

Preparation of (S)-2-Substituted Succinates by Stereospecific Reductions of Fumarate and Derivatives with Resting Cells of Clostridium formicoaceticum

Fumarate derivatives have been reduced to (S)-2-methylsuccinate 2a, (S)-2-ethylsuccinate 3a and (S)-2-chlorosuccinate 4a in up to 1 M concentrations with Clostridium formicoaceticum.Formate was the electron donor and viologens or anthraquinone-2,6-disulphonate acted as artificial electron mediators.Reductions with freeze-dried cells in 2H2O-buffers led to the (2R,3S)--dideuterated succinate derivatives.The productivity numbers ranged from 450 to 5000 and the enantiomeric excess of all (S)-2-substituted succinates was >/= 99percent.