41378-27-2 Usage
General Description
3-N-ethylaminoacetanilide is a chemical compound that consists of an acetanilide molecule with an attached ethylamino group at the 3-position of the aromatic ring. It is primarily used in the synthesis of pharmaceuticals and as an intermediate in organic chemistry reactions. The ethylamino group provides flexibility and steric hindrance to the molecule, making it a useful building block in drug design and organic synthesis. 3-N-ethylaminoacetanilide has potential biological activity and is under investigation for its role in various pharmacological applications. Its unique structure and properties make it a valuable tool in medicinal chemistry and drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 41378-27-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,1,3,7 and 8 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 41378-27:
(7*4)+(6*1)+(5*3)+(4*7)+(3*8)+(2*2)+(1*7)=112
112 % 10 = 2
So 41378-27-2 is a valid CAS Registry Number.
InChI:InChI=1/C10H14N2O/c1-3-11-9-5-4-6-10(7-9)12-8(2)13/h4-7,11H,3H2,1-2H3,(H,12,13)
41378-27-2Relevant articles and documents
Tuning thiol addition to squaraines by ortho-substitution and the use of serum albumin
Diehl, Katharine L.,Bachman, J. Logan,Anslyn, Eric V.
, p. 316 - 324 (2017/03/02)
Tuning the reactivity of squaraine dyes toward nucleophilic addition of thiols was investigated. A series of water soluble, aniline-derived squaraines were synthesized with various ortho substitutions to the squaraine ring. As hypothesized, we found that placing moderately electron donating groups in the ortho position conveyed intermediate reactivity to thiols between the essentially non-reactive hydroxyl-substituted squaraines and very reactive non-substituted squaraines. Furthermore, serum albumin was tested for its influence on the addition of thiols to the squaraines. The dyes bind in the hydrophobic cavities of the protein, and thus we expected serum albumin to affect the squaraines' reactivity. Rather than a protective effect by the protein, we found a cooperative effect for thiol addition.
