41378-27-2 Usage
Uses
Used in Pharmaceutical Synthesis:
3-N-ETHYLAMINOACETANILIDE is used as a key intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs with improved efficacy and selectivity.
Used in Organic Chemistry Reactions:
In the field of organic chemistry, 3-N-ETHYLAMINOACETANILIDE serves as a versatile intermediate, facilitating a range of chemical reactions that can lead to the creation of diverse organic compounds.
Used in Drug Design:
3-N-ETHYLAMINOACETANILIDE is utilized as a structural component in drug design, where its unique properties can enhance the pharmacological profile of new drug candidates, potentially leading to more effective treatments.
Used in Medicinal Chemistry Research:
In medicinal chemistry, 3-N-ETHYLAMINOACETANILIDE is employed in research to explore its potential biological activity and role in pharmacological applications, contributing to the advancement of drug discovery and development.
Check Digit Verification of cas no
The CAS Registry Mumber 41378-27-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,1,3,7 and 8 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 41378-27:
(7*4)+(6*1)+(5*3)+(4*7)+(3*8)+(2*2)+(1*7)=112
112 % 10 = 2
So 41378-27-2 is a valid CAS Registry Number.
InChI:InChI=1/C10H14N2O/c1-3-11-9-5-4-6-10(7-9)12-8(2)13/h4-7,11H,3H2,1-2H3,(H,12,13)
41378-27-2Relevant academic research and scientific papers
Tuning thiol addition to squaraines by ortho-substitution and the use of serum albumin
Diehl, Katharine L.,Bachman, J. Logan,Anslyn, Eric V.
, p. 316 - 324 (2017/03/02)
Tuning the reactivity of squaraine dyes toward nucleophilic addition of thiols was investigated. A series of water soluble, aniline-derived squaraines were synthesized with various ortho substitutions to the squaraine ring. As hypothesized, we found that placing moderately electron donating groups in the ortho position conveyed intermediate reactivity to thiols between the essentially non-reactive hydroxyl-substituted squaraines and very reactive non-substituted squaraines. Furthermore, serum albumin was tested for its influence on the addition of thiols to the squaraines. The dyes bind in the hydrophobic cavities of the protein, and thus we expected serum albumin to affect the squaraines' reactivity. Rather than a protective effect by the protein, we found a cooperative effect for thiol addition.
