41441-41-2

Basic information

• Product Name: BETA-(NITROMETHYL)-BENZENEPROPANOIC ACID
• Synonyms: BETA-(NITROMETHYL)-BENZENEPROPANOIC ACID
• CAS NO: 41441-41-2
• Molecular Formula: C₁₀H₁₁NO₄
• Molecular Weight: 209.2
• Mol File: 41441-41-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: BETA-(NITROMETHYL)-BENZENEPROPANOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: BETA-(NITROMETHYL)-BENZENEPROPANOIC ACID(41441-41-2)
• EPA Substance Registry System: BETA-(NITROMETHYL)-BENZENEPROPANOIC ACID(41441-41-2)

Safety Data

• Hazardous Substances Data: 41441-41-2(Hazardous Substances Data)

Upstream product

• 41441-40-1 ethyl 3-phenyl-4-nitrobutanoate 
• 14371-10-9 (E)-3-phenylpropenal 
• 1002103-54-9 4-nitro-3-phenylbutanal 
• 34687-03-1 4-nitro-3-phenylbutanoic acid methyl ester 
• 103-26-4 methyl cinnamate 
• 100-52-7 benzaldehyde 
• 100-51-6 benzyl alcohol 

Downstream Products

• 1078-21-3 4-amino-3-phenylbutanoic acid 
• 34687-03-1 4-nitro-3-phenylbutanoic acid methyl ester 
• 1215863-49-2 C₁₀H₉NO₂ 

Relevant articles and documents

Telescoped Continuous Flow Synthesis of Optically Active γ-Nitrobutyric Acids as Key Intermediates of Baclofen, Phenibut, and Fluorophenibut

The two-step flow asymmetric synthesis of chiral γ-nitrobutyric acids as key intermediates of the GABA analogues baclofen, phenibut, and fluorophenibut is reported on a multigram scale. The telescoped process comprises an enantioselective Michael-type add

Intermediates for the synthesis of 4-substituted proline derivatives

A chemoenzymatic synthesis of a series of 2-hydroxy-5-nitro-4-substituted esters is described that uses two biotransformations in a single-pot process in which a kinetic resolution/reduction occurs. The products are valuable intermediates for the preparation of 4-substituted prolines and 5-substituted 3-hydroxypiperidinones as illustrated by the preparation of (2R,4R)-4- methylproline and (3S,5R)-3-hydroxy-5-methylpiperidinone. Georg Thieme Verlag Stuttgart · New York.