41447-16-9

Usage

Uses

Due to the limited information available on (+)-N-Methylallosedridine, its uses are not well-defined. However, based on its classification as an isoquinoline alkaloid, it can be inferred that it may have potential applications in various fields, such as:
Used in Pharmaceutical Industry:
(+)-N-Methylallosedridine could be used as a pharmaceutical compound for [application reason], given its classification as an isoquinoline alkaloid. Alkaloids are often found to have biological activities, which could be harnessed for therapeutic purposes.
Used in Chemical Research:
(+)-N-Methylallosedridine could be used as a research compound for [application reason], as understanding its properties and potential interactions with other molecules could contribute to the development of new chemical entities or insights into the structure and function of isoquinoline alkaloids.

Upstream product

• 190383-58-5 [2R-(2R)]-1-benzyloxycarbonyl-2-(2,3-epoxypropyl)piperidine 
• 863768-20-1 (2S,2'R)-1-[N(1')-(tert-butoxycarbonyl)piperidin-2'-yl]propan-2-ol 
• 175857-65-5 2-(diphenylphosphinoyl)piperidine 
• 50-00-0 formaldehyd 
• 77-78-1 dimethyl sulfate 
• 184535-05-5 (R)-1-benzyloxycarbonyl-2-(2-propenyl)piperidine 
• 223477-90-5 1-tert-butoxycarboxy-2-diphenylphosphinylpiperidine 
• 522-33-8 Tripiperidin 
• 847905-90-2 3-methyl-4,6,7,8-tetrahydro-3H-pyrido[1,2-c][1,3]oxazin-1-one 
• 190383-54-1 [2R-(2R)]-1-benzyloxycarbonyl-2-(2,3-dihydroxypropyl)piperidine 
• 639458-46-1 (R)-2-(2-oxo-ethyl)-piperidine-1-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

Synthesis of bicyclic carbamates as precursors of Sedum alkaloid derivatives

Synthesis of a N-Boc-protected piperidin-2-yl phosphine oxide starting from piperidine in three steps, followed by olefination using a variety of α,β-unsaturated aldehydes resulted in tert-butyl 2-(2′- alkenylidene)piperidine-1-carboxylates in high yields

Short enantioselective synthesis of sedridines, ethylnorlobelols and coniine via reagent-based differentiation

The preparation of collections of structurally diverse small molecules is a useful tool for studying biology and medicine with chemistry. Herein, we demonstrate the versatility of the pure enantiomers of 2-(2-oxo-ethyl)- piperidine-1-carboxylic acid tert-butyl ester to prepare the biological active alkaloids sedridine, allosedridine, methylsedridine, methylallosedridine, ethylnorlobelol, and coniine in two steps and in a stereoselective way via a reagent-based differentiation. The described syntheses are a demonstration of the versatility of 2-(2-oxo-ethyl)-piperidine-1-carboxylic acid tert-butyl esters as chiral building blocks.

A new synthesis of all four stereoisomers of 2-(2,3- dihydroxypropyl)piperidine via iterative asymmetric dihydroxylation to cause enantiomeric enhancement. Application to asymmetric synthesis of naturally occurring piperidine-related alkaloids

Both enantiomers of 2-(2-propenyl)piperidine 1 (76-88% ee), prepared via the first asymmetric dihydroxylation (AD) of 5-hexenyl azide, underwent the second AD to provide all four of the stereoisomeric 2-(2,3- dihydroxypropyl)piperidines 2 with enantiomeric enhancement.(>98% ee). An asymmetric synthesis, starting from 2, of several 2-(2- hydroxyalkyl)piperidine alkaloids [(-)halosaline, (+)-N-methylallosedridine, (+)-8-ethylnorlobelol, (+)-sedridine, (+)-allosedridine, (-)allosedridine, and (+)-N-methylsedridine] and the ant defense alkaloids [(+)-tetraponerine-3 (T-3), T-4, T-7, and T-8] is demonstrated.

A general entry to 2-(2-hydroxyalkyl)piperidines via iterative asymmetric dihydroxylation to cause enantiomeric enhancement

Both enantiomers of 2-(2-propenyl)piperidine (1) (76-88% ee), prepared via the first AD of 5-hexenyl azide, underwent the second AD to provide all of the four stereoisomeric 2-(2-hydroxypropyl)piperidines (2) with enantiomeric enhancement (>98 ee). An asy