4146-04-7

Basic information

• Product Name: D/L-NORVALINOL
• Synonyms: DL-2-AMINO-1-PENTANOL;D/L-NORVALINOL;2-AMINO-1-PENTANOL;2-AMINOPENTANOL;2-aminopentan-1-ol;2-azanylpentan-1-ol;DL-2-Amino-1-pentanol 97%
• CAS NO: 4146-04-7
• Molecular Formula: C₅H₁₃NO
• Molecular Weight: 103.16
• Product Categories: Amino Alcohols;Organic Building Blocks;Oxygen Compounds
• Mol File: 4146-04-7.mol
• Article Data: 6

Chemical Properties

• Melting Point: 29.84°C (estimate)
• Boiling Point: 194-195 °C(lit.)
• Flash Point: 203 °F
• Appearance: /
• Density: 0.922 g/mL at 25 °C(lit.)
• Vapor Pressure: 161mmHg at 25°C
• Refractive Index: n20/D 1.4511(lit.)
• CAS DataBase Reference: D/L-NORVALINOL(CAS DataBase Reference)
• NIST Chemistry Reference: D/L-NORVALINOL(4146-04-7)
• EPA Substance Registry System: D/L-NORVALINOL(4146-04-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• RIDADR: UN 2735 8/PG 3
• WGK Germany: 3
• Hazardous Substances Data: 4146-04-7(Hazardous Substances Data)

Usage

Uses

DL-2-Amino-1-pentanol was used as solvent to evaluate lyotropic liquid crystal mesophases of hexadecylpyridinium bromide (C16PyrBr) by cross-polarised optical microscopy (CPOM).

InChI:InChI=1/C4H9N/c1-3-4-5-2/h3,5H,1,4H2,2H3

Upstream product

• 132949-27-0 1-((S)-2-Methoxy-1-phenyl-ethoxymethyl)-butylamine 
• 10047-10-6 norvaline methyl ester hydrochloride 
• 13893-43-1 ethyl 2-aminopentanoate 
• 760-78-1 2-aminopentanoic acid 
• 516-06-3 D,L-valine 
• 2899-90-3 2-nitro-pentan-1-ol 
• 132949-24-7 N-benzyloxy-1-((S)-2-methoxy-1-phenylethoxy)-4-penten-2-ylamine 

Downstream Products

• 145842-46-2 (+/-)-2-(acetylamino)pentyl acetate 
• 4293-54-3 2-acetylaminopentan-1-ol 
• 259102-97-1 2-[[7-Chloro-5-[(phenylmethyl)thio]thiazolo[4,5-d]pyrimidin-2-yl]amino]-1-pentanol 
• 22724-81-8 L-norvalinol 
• 80696-30-6 (2R)-2-aminopentan-1-ol 
• 137160-75-9 N-(1-Hydroxymethyl-butyl)-butyramide 
• 69451-78-1 Nicotinic acid 2-[(pyridine-3-carbonyl)-amino]-pentyl ester 
• 64271-01-8 2,5-di-n-propylpyrazine 
• 179684-02-7 2-(Boc-amino)-1-pentanol 
• 1617545-92-2 2-[6-(5-chloro-2-fluoro-phenyl)-pyrazin-2-ylamino]-pentan-1-ol 
• 145799-43-5 (R,S)-O-benzyl-N-(1-(hydroxymethyl)butyl)carbamate 
• 19856-55-4 3-propyl-4-[3-(3,4,5-trimethoxy-phenyl)-acryloyl]-morpholine 
• 19856-81-6 3-propyl-morpholine 
• 189251-22-7 N-[2-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-4-methyl-N-(1-propyl-hept-6-enyl)-benzenesulfonamide 

Relevant articles and documents

A catalyst-free, convenient construction of eight-membered [1,4]oxazocane-5,8-dione heterocycles from aminoethanols with divinyl succinate

A convenient protocol for the synthesis of [1,4]oxazocane-5,8-dione heterocycles by direct cyclization using 2-substituted aminoethanols and divinyl succinate without any catalysts and additives was established. This strategy is quite simple and effective to obtain eight-membered rings incorporating lactone and lactam functional groups. Georg Thieme Verlag Stuttgart.

Enantioselective synthesis and absolute configuration of (-)-1-(benzofuran-2-yl)-2-propylaminopentane, ((-)-BPAP), a highly potent and selective catecholaminergic activity enhancer

Enantioselective synthesis and absolute configuration of (-)-1-(benzofuran-2-yl)-2-propylaminopentane ((-)-BPAP), which is a highly potent and selective catecholaminergic activity enhancer (CAE) substance, are described. The synthetic approach consists of the coupling reaction of benzofuran with (R)-N-tosyl-2-propylazirizine or (R)-N-methoxy-N-methylnorvaliamide, followed by appropriate modifications of the resulting coupling products. As the results, (-)-BPAP turned out to have the R configuration, which was finally confirmed by X-ray crystallographic analysis.

The use of alpha-amino acids in the synthesis of derivatives of 2-aminoethanethiol as potential antiradiation agents.

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