41498-18-4

Upstream product

• 50-00-0 formaldehyd 
• 13294-73-0 1-tert-butyl-4-methylenecyclohexane 
• 75-24-1 trimethylaluminum 
• 54280-91-0 1-<(ethoxycarbonyl)methyl>-4-tert-butylcyclohexanol 
• 1240401-57-3 2-(4-tert-butylcyclohexylidene)ethyl picolinate 
• 557-20-0 diethylzinc 
• 920-39-8 isopropylmagnesium bromide 
• 129518-99-6 ethyl (4-tert-butylcyclohexylidene)acetate 
• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 98-53-3 4-tercbutyl-cyclohexanone 
• 28835-96-3 (4-tert-butylcyclohexylidene)acetic acid 
• 104173-06-0 C₁₈H₂₇NOS 
• 140402-04-6 [2-(4-tert-Butyl-cyclohexylidene)-ethyl]-isopropoxy-dimethyl-silane 
• 13278-24-5 acide hydroxy-1 tertiobutyl-4 cyclohexane-acetique 

Downstream Products

• 77928-00-8 (4-tert-Butyl-1-vinyl-cyclohexyl)-hydroxy-acetic acid 
• 1240401-57-3 2-(4-tert-butylcyclohexylidene)ethyl picolinate 
• 1332864-90-0 tert-butyl 1-(2-(4-tert-butylcyclohexylidene)ethyl)hydrazinecarboxylate 
• 1333113-76-0 (E)-(tert-butyl) 2-(4-(tert-butyl)-1-vinylcyclohexyl)diazenecarboxylate 
• 1332864-89-7 C₂₅H₃₀Cl₄N₂O₄ 
• 75646-58-1 2-(4'-t-butyl-1'-vinylcyclohex-1'-yl)-2-(pyrrolidin-1''-yl)acetonitrile 
• 40585-98-6 cis-4-t-butylcyclohexane-1-carbaldehyde 
• 40585-97-5 trans-4-t-butylcyclohexane-1-carbaldehyde 
• 105962-03-6 (1E)-2-<4'-(tert-butyl)cyclohex-1'-enyl>-N,N-dimethylethen-1-ylamine 
• 503003-85-8 dithiocarbonic acid S-(4-tert-butyl-1-vinyl-cyclohexyl) ester S-methyl ester 
• 503003-69-8 C₁₂H₂₁NOS 
• 503003-71-2 C₁₂H₂₁NOS 
• 503003-89-2 4-tert-butyl-1-vinyl-cyclohexanethiol 
• 77927-90-3 [2-(4-tert-Butyl-cyclohexylidene)-ethoxy]-acetic acid 

Relevant academic research and scientific papers

Diastereoselectivity in the Overman rearrangement of O-cyclohexylideneethylimidates

Conformationally biased cyclohexylideneethanols were prepared and converted to trichloroacetimidates, which then were subjected to the thermal Overman rearrangement. The rearrangement of axially unshielded imidates was unselective, providing isomeric amid

Synthesis and Biological Activity of New 4-tert-Butylcyclohexanone Derivatives

In the synthesis performed in this study, derivatives of 4-tert-butylcyclohexanone 1 were obtained using typical reactions of organic synthesis. The bioactivity of the selected compounds was evaluated. 1-(Bromomethyl)-8-tert-butyl-2-oxaspiro[4.5]decan-3-o

Construction of a quaternary carbon at the carbonyl carbon of the cyclohexane ring

High SN2′ selectivity in the allylic substitution of cyclohexylidene ethyl picolinates with copper reagents prepared from RMgBr and CuBr·Me2S was realized by addition of ZnX2 (X = I, Br, Cl). Furthermore, ZnX2 accelerated the reaction with the bulky iPr reagent. The Royal Society of Chemistry 2010.

Thioepoxide formation by ring closure of allylthiyl radicals - A novel rearrangement of allylic thionitrites

Tertiary allylic thionitrites undergo thermal rearrangement to α,β-episulfide nitroso dimers via ring closure of allylthiyl radicals.

External chiral ligand-mediated enantioselective peterson reaction of α-trimethylsilanylacetate with substituted cyclohexanones

(equationpresented) The asymmetric Peterson reaction of an α-trimethylsilanylacetate with 4-substituted and 3,5-disubstituted cyclohexanones was mediated by an external chiral tridentate ligand to give the corresponding olefins with an axial chirality in

Asymmetric Wittig reaction of chiral arsonium ylides - I. Asymmetric olefination of 4-substituted cyclohexanones

Asymmetric Wittig-type olefination of 4-substituted cyclohexanones with chiral ligand-modified stable arsonium ylides has been examined. The 8-phenylmenthol-derived chiral arsonium ylide of 4 reacted with prochiral ketones 9a-d at -15°C to give the 4-substituted cyclohexylideneacetates 11a-d in 58-69% yield and in up to 80% diastereomeric excess (de).

The asymmetric Horner-Emmons reaction using a benzopyrano-isoxazolidine auxiliary

The asymmetric Horner-Emmons reaction of the phosphonate derived from a chiral benzopyrano-isoxazolidine (with 4-substituted cyclohexanones) proceeded in high diastereoselectivity with the aid of KHMDS and 18-crown-6 ether. Enantiomerically pure, axially dissymmetric cyclohexylidene alcohols, aldehydes and ketones were obtained from the diastereomerically pure Horner-Emmons products in a single step.

Double Metal-Catalyzed Cross-Coupling Reactions of Alkenyl Sulfoximines with Diorganozinc Reagents: Synthesis of Optically Active Axial Chiral Allylic Silanes

Nickel- and magnesium-catalyzed cross-coupling reaction of the alkenyl sulfoximine 5 with the pure diorganozinc reagents 6a and 6b gave the optically active allylic silanes 7a and 7b, respectively.Single metal catalysis was sufficient for the substitution

98. A Regioselective Cyclohexannulation Procedure via Dienamine Cycloaddition. Synthesis of Functionalised Decalins

A regioselective cyclohexannulation procedure, whose key step involves the cycloaddition of dienamines 12-24 with methyl acrylate, allows the conversion of cycloalkanones 1-11 to bicyclic dienoates 25-37.The chemistry of 26 is briefly examined and, in the context of organoleptic studies concerning functionalised 5,5,9-trimethyldecalins, the transformation of 37 to ketones 44 and 46 as well as to acetates 53-56 is described.

Reactions of the Formaldehyde-Trimethylaluminum Complex with Alkenes

Reaction of CH2O*Me3Al with electron-rich alkenes gives a zwitterion that reacts further to give homoallylic alcohols (ene adducts), allylic alcohols, and the product of cis addition of a hydroxymethyl and a methyl group to the double bond.The stereochemistry and effect of alkene structure on the nature of the reaction are examined.