4151-47-7

Upstream product

• 4151-62-6 4-amino-2-(tert-butyl)phenol 
• 108-24-7 acetic anhydride 
• 37405-22-4 2-(1,1-dimethylethyl)-2,5-cyclohexadiene-1,4-dione 4-oxime 
• 96-76-4 2,4-di-tert-Butylphenol 
• 35787-71-4 thianthrene cation radical perchlorate 
• 75-05-8 acetonitrile 
• 88-18-6 2-tert-Butylphenol 

Downstream Products

• 749168-68-1 N-(3-tert-Butyl-5-diethylaminomethyl-4-hydroxy-phenyl)-acetamide 
• 240130-29-4 N-[3-tert-butyl-5-(tert-butylamino-methyl)-4-hydroxy-phenyl]-acetamide 
• 107244-68-8 4-Amino-2-tert-butyl-6-diethylaminomethyl-phenol; hydrochloride 
• 107244-85-9 2-tert-Butyl-4-(7-chloro-1-oxy-quinolin-4-ylamino)-6-diethylaminomethyl-phenol 
• 107244-77-9 2-tert-Butyl-4-(7-chloro-quinolin-4-ylamino)-6-diethylaminomethyl-phenol 

Relevant academic research and scientific papers

Reactions of Phenols with Thianthrene Cation Radical

The phenols 2-R1-6-R2-phenol 1a-g in which R1 = R2 = tert-butyl, methyl, isopropyl, Cl, Br, F, and H reacted with thianthrene cation radical perchlorate (TH+ClO4-) to give 5-(4-hydroxyaryl)thianthreniumyl perchlorates 2a-g in good yield. o-Allylphenol (1i) behaved similarly. o-tert-Butylphenol (1h) gave both 5-(3-tert-butyl-4-hydroxyphenyl)thianthreniumyl perchlorate (2h) and a quinonoidal perchlorate (3), namely, 5-(3-thianthreniumyl-5-tert-butyl-6-oxo-2,4-cyclohexadien-1-ylidene)-5,5-dihydrothianthrene perchlorate.The 2,6-di-tert-butyl-4-R3-phenols 4a-c, R3 = tert-butyl, methoxy, and methyl, reacted with Th+ClO4- in nitrile solvents (RCN) to give 2-R-5-R3-7-tert-butylbenzoxazoles 5a-e.The tert-butyl group that was displaced by RCN in forming 5 was converted into t-BuNHCOR (8), tert-butyl alcohol, and isobutene.In contrast, 2-tert-butyl-4,6-dimethylphenol (9) gave, in CH3CN, 4-tert-butyl-2,5,7-trimethylbenzoxazole (11), that is, with migration of the displaced tert-butyl group.The reactions of 4-tert-butylphenol (14) and 2,4-di-tert-butylphenol (17) are also described.