41526-55-0

Upstream product

• 6836-19-7 7-Methoxy-1-tetralone 
• 100-52-7 benzaldehyde 

Downstream Products

• 124049-62-3 2-Benzyl-7-methoxy-3,4-dihydro-2H-naphthalen-1-one 
• 418798-38-6 9-methoxy-4-phenyl-3,4,5,6-tetrahydro-1H-benzo[h]quinazoline-2-thione 
• 360766-97-8 1-hydroxy-2-benzyl-7-methoxy-1,2,3,4-tetrahydro-1-naphthylacetonitrile 
• 360767-01-7 (2-benzyl-1-hydroxy-7-methoxy-1,2-dihydro-naphthalen-1-yl)-acetonitrile 
• 360767-03-9 2-benzyl-7-methoxy-1-naphthylacetonitrile 

Relevant academic research and scientific papers

Discovery of 3,3a,4,5-tetrahydro-2H-benzo[g]indazole containing quinoxaline derivatives as novel EGFR/HER-2 dual inhibitors

In the present study, twenty-five pyrazole-quinoxaline derivatives (4a-4y) were designed and synthesized, and their biological activity as potential EGFR or HER-2 kinase inhibitors was evaluated. Among them, compound 4l displayed better antiproliferative

Synthesis of naphthalenic melatonin receptor ligands

A highly efficient and versatile synthetic approach to the synthesis of naphthalenic analogs of melatonin, compound 7, and its 2-alkyl substituted analog 8 is described. This approach features the novel synthesis of substituted 1-naphthyl acetonitrile 12 and 19 by nucleophilic addition of LiCH2CN to substituted 1-tetralone, followed by aromatization via a 2-step reaction sequence, dehydrogenation with DDQ and TsOH catalyzed dehydration.