415929-58-7

Upstream product

• 109-01-3 1-methyl-piperazine 
• 4397-53-9 p-benzyloxybenzaldehyde 
• 505-66-8 1,4-Diazacycloheptane 
• 4318-37-0 1-Methylhomopiperazine 
• 103-76-4 1-(2-hydroxyethyl)piperazine 
• 13349-82-1 1-[2-(2-hydroxyethoxy)ethyl]piperazine 
• 4897-50-1 4-piperidinopiperidin 
• 2759-28-6 1-phenylmethylpiperazine 
• 303-26-4 N-(4-chlorobenzhydryl)piperazine 
• 51207-66-0 (S)-2-(1-pyrrolidinylmethyl)pyrrolidine 
• 103-55-9 N,N-dimethyl-N'-benzyl-1,2-ethanediamine 
• 5004-07-9 4-(1-pyrrolidinyl)piperidine 
• 2252-63-3 1-(4-Fluorophenyl)piperazine 
• 1011-15-0 1-(o-fluorophenyl)piperazine 

Relevant academic research and scientific papers

Anthracene-rhodium complexes with metal coordination at the central ring-a new class of catalysts for reductive amination

A new class of anthracene complexes with a metal coordinated at the central ring was applied in catalysis for the first time. As a result, a simple and efficient protocol for reductive amination that involves CO as a reducing agent has been developed. The rhodium complex [(cyclooctadiene)Rh(C10H4Me2(OMe)4)]+ (1 mol%) catalyses such reactions under mild conditions (40-130 °C) and produces a variety of amines in good yields (74-95%) without affecting the functional groups. The protocol is acceptable for all combinations of aldehydes (aromatic and aliphatic), ketones (aromatic and aliphatic) and amines (aromatic and aliphatic; primary and secondary).

METHODS AND COMPOSITIONS COMPRISING DIAMINES AS NEW ANTI-TUBERCULAR THERAPEUTICS

Methods and compositions for treating disease caused by infectious agents, particularly tuberculosis. In particular, methods and compositions comprising novel diamine compositions for the treatment of infectious diseases are provided. In one embodiment, these methods and compositions are used for the treatment of mycobacterial infections, including, but not limited to, tuberculosis.