41634-38-2

Upstream product

• 186581-53-3 diazomethane 
• 38487-11-5 diphenylmethane-2,2'-dicarboxylic acid 
• 2222-33-5 dibenzosuberenon 
• 109407-76-3 (2-carboxyphenyl)phtalide 
• 72872-62-9 o,o'-benzil dicarboxylic acid 
• 573-32-0 benzophenone-2,2'-dicarboxylic acid 
• 67-56-1 methanol 

Downstream Products

• 38059-08-4 bis<(2-hydroxymethyl)phenyl>methane 
• 108059-38-7 Dibenzocycloocten-5,7(6H,12H)-dion 
• 108059-39-8 2,2'-Methylenbisacetophenon 
• 108059-37-6 7,12-Dihydro-7,7-dimethyl-5H-dibenzoxocin-5-on 
• 108059-40-1 7,12-Dihydro-7-hydroxy-7-methyldibenzocycloocten-5(6H)-on 
• 108059-42-3 2-<2-(1-Hydroxy-1-methylethyl)benzyl>acetophenon 
• 108059-41-2 2-<2-(1-Hydroxy-1-methylethyl)benzyl>benzoesaeure-methylester 
• 108059-36-5 2,2'-Methylenbis(α,α-dimethylbenzylalkohol) 
• 51615-11-3 Bis<(2-bromomethyl)phenyl>methane 

Relevant academic research and scientific papers

STUDIES ON THE SYNTHESIS OF HETEROCYCLIC COMPOUNDS. XVII. THE PREPARATION OF MACROCYCLIC POLYESTER LIGANDS CONTAINING THE 2,2'-BIS(HYDROXYMETHYL)DIPHENYLMETHANE SUBCYCLIC UNIT

Novel macrocyclic tetraester ligands containing the 2,2'-bid(hydroxymethyl)diphenylmethane subcyclic unit have been prepared using an intermediate dioxastannocin with diacyl chlorides.The products were characterized by analitycal and spectroscopic (IR and NMR) data.The MS spectra of these ligands have been studied and the fragmentation patterns and structures of the main ions are described.

Dibenzocyclooctene-, Dibenzochalcocine-, and Diarenochalconinediones

2,2'-Oxybis-, -thiobis-, and -methylenebisbenzoic esters 2a-c react with methyllithium in ether to give low yields of 5H-dibenzochalcocine-5,7(6H)-diones 6a, 7a, and dibenzocyclooctene-5,7(6H,12H)-dione (8), respectively.Very good yields of such heterocycles with oxygen (6a-h, 37), sulfur (7a-h, 38) and selenium (36) as key atom are obtained when diaryl ethers (21, 22, 25), -sulfides (27, 29, 30), and -selenides (33) that contain 2'-acetyl- (or -propionyl-) and 2-methoxycarbonyl groups are treated with sodium hydride in boiling toluene.Analogously are prepared the dibenzoxonine-11,13(6H,12H)diones 62a-c and 7H-benzonaphthothionine-7,9-(8H)-dione (65) which are expanded by one ring member.In the analogous reaction of a corresponding benzophenone derivative 35, spiro-3(2H),3'-dione (41) is formed in a tandem reaction. - Under phase transfer conditions the dibenzochalcocinediones 6, 7, 36 and also the corresponding nitrogen cycles 5 react to give mixtures of C- (42-45) and O-alkyl derivatives (46-49).Methyllithium and diisobutylaluminium hydride provide the carbinols 50-54.With bromine and SO2Cl2, respectively, the methylene group is mono- or dihalogenated to the products 56, 57; defined nitration was only possible for the oxacycle 6a.