41637-08-5

Upstream product

• 76121-44-3 K⁽¹⁺⁾*Pt(C₆H₅NH₂)Cl₃^(1-)=K(Pt(C₆H₅NH₂)Cl₃) 
• 10025-99-7 potassium tetrachloroplatinate(II) 
• 62-53-3 aniline 
• 142-04-1 aniline hydrochloride 
• 784984-93-6 {Ptan₄}⁽²⁺⁾ 

Downstream Products

• 41637-08-5 trans-{Pt(aniline)2Cl₂} 

Relevant academic research and scientific papers

CATALYST FOR SYNTHESIZING METHANOL OR ITS PRECURSOR, METHOD FOR PREPARING THE CATALYST AND METHOD FOR PRODUCING METHANOL OR ITS PRECURSOR USING THE CATALYST

Disclosed is a novel catalyst having amine ligands for synthesizing methanol or its precursor. When the catalyst is allowed to react with an alkane in the presence of an acid, at least one C—H bond of the alkane is catalytically oxidized. Therefore, the catalyst is suitable for use in forming an alkyl ester from an alkane.

The synthesis, structure-toxicity relationship of cisplatin derivatives for the mechanism research of cisplatin-induced nephrotoxicity

Cisplatin is a widely used antineoplastic drug, while its nephrotoxicity limits the clinical application. Although several mechanisms contributing to nephrotoxicity have been reported, the direct protein targets are unclear. Herein we reported the synthesis of 29 cisplatin derivatives and the structure-toxicity relationship (STR) of these compounds with MTT assay in human renal proximal tubule cells (HK-2) and pig kidney epithelial cells (LLC-PK1). To the best of our knowledge, this study represented the first report regarding the structure-toxicity relationship (STR) of cisplatin derivatives. The potency of biotin-pyridine conjugated derivative 3 met the requirement for target identification, and the preliminary chemical proteomics results suggested that it is a promising tool for further target identification of cisplatin-induced nephrotoxicity.

Cis- and trans-platinum complexes of anilines. A study of isormerization reactions

Cis- and trans-[PtL2Cl2] (where L = aniline, 2,5-dimethylaniline and p-toluidine) have been synthesized. The cis-compounds can be isolated isomerically pure from the reaction of K[PtLCl3] and L in a mixture of water and ethanol. The trans-isomers are obtained from the isomerization of the cis-compounds. The isomers can be identified from their infrared spectra. The isomer pair, [Pt(2,5-dimethyl-aniline)2Cl2] respond to Kurnakov's test in acetone solution at room temperature. Trans-[Pt(2,5-dimethylaniline)2(thiourea)2] Cl2 has been characterized.

THE INFRARED SPECTRA OF ANILINE COMPLEXES OF PLATINUM(II) HALIDES AND NITRITE

The infrared spectra (4000-90 cm-1) of the complexes cis- and trans- (an=aniline; X=Cl, Br, I, NO2) and their aniline-d5 analogues are determined.For the complexes cis- and trans-, the spectra of the 15N-labelled species