41692-50-6

Upstream product

• 64-17-5 ethanol 
• 4331-54-8 4-methylcyclohexanecarboxylic acid 
• 99-94-5 p-Toluic acid 
• 7133-31-5 4-methylcyclohexanecarboxylic acid ethyl ester 
• 53695-40-2 Diethyl 4-Methylcyclohexane-1,1-dicarboxylate 
• 934-67-8 trans-4-methylcyclohexanecarboxylic acid 

Downstream Products

• 34885-03-5 (4-methylcyclohexyl)methanol 
• 3937-49-3 (trans-4-methylcyclohexyl)methanol 
• 498-81-7 p-menthan-8-ol 

Relevant academic research and scientific papers

Esters of 17 α-ethynyl 19-nor-testosterone and 17 α-ethynyl-18-homo-19-nor-testosterone and pharmaceutical compositions containing the same

Esters of 17 α-ethynyl 19-nor-testosterone and 17 α-ethynyl-18-homo-19-nor-testosterone and the 3-oximes thereof having long-active contraceptive activity.

Stereochemistry of Decarbalkoxylation of Cyclic Geminal Diesters Effected by Water and Lithium Chloride in Me2SO

The stereochemical consequences of the decarbalkoxylation of cyclic geminal diesters by LiCl-H2O-Me2SO have been examined.The norbornene diester 13 and the norbornane diester 16 lead predominantly to the exoesters 14 and 17, respectively.The 2-methylcyclohexane diester 22 leads to esters containing more cis (23) than trans (24) isomer.The diesters 19,25, and 28 lead to nearly equal amounts of the cis and trans esters.In these latter cases,the enolates generated from the esters (via LDA) are protonated in a nonstereoselective fashion on quenching with water.This is suggestive of an enolate intermediate in the decarbalkoxylation reaction.The implications of these sterochemical results are discussed.