934-67-8

Basic information

• Product Name: cis-4-methylcyclohexanecarboxylic acid
• Synonyms: cis-4-methylcyclohexanecarboxylic acid;(1α,4α)-4-Methylcyclohexanecarboxylic acid
• CAS NO: 934-67-8
• Molecular Formula: C₈H₁₄O₂
• Molecular Weight: 142.19556
• EINECS: 213-289-5
• Mol File: 934-67-8.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 247.5°Cat760mmHg
• Flash Point: 110.7°C
• Appearance: /
• Density: 1.025g/cm³
• Vapor Pressure: 0.008mmHg at 25°C
• Refractive Index: 1.467
• CAS DataBase Reference: cis-4-methylcyclohexanecarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: cis-4-methylcyclohexanecarboxylic acid(934-67-8)
• EPA Substance Registry System: cis-4-methylcyclohexanecarboxylic acid(934-67-8)

Safety Data

• Hazardous Substances Data: 934-67-8(Hazardous Substances Data)

Usage

General Description

Cis-4-methylcyclohexanecarboxylic acid is a chemical compound with a molecular formula of C8H14O2. It is a carboxylic acid, which means it contains a carboxyl group (-COOH) attached to a cyclohexane ring. cis-4-methylcyclohexanecarboxylic acid exists in a cis conformation, meaning that the substituent groups are located on the same side of the ring. It is commonly used as a building block in organic synthesis and can be found in various pharmaceutical and agrochemical products. Cis-4-methylcyclohexanecarboxylic acid possesses a unique structure and functional groups that make it useful for the production of diverse chemical compounds.

InChI:InChI=1/C8H14O2/c1-6-2-4-7(5-3-6)8(9)10/h6-7H,2-5H2,1H3,(H,9,10)/t6-,7+

Upstream product

• 29886-34-8 4-methyl-1-cyclohexanecarboxylic acid methyl ester 
• 201230-82-2 carbon monoxide 
• 82166-21-0 methyl cyclohexane 
• 51181-40-9 methyl 4-methyl-1-cyclohexanecarboxylate 
• 64-19-7 acetic acid 
• 99-94-5 p-Toluic acid 
• 124-38-9 carbon dioxide 
• 931-68-0 1-chloro-4-methylcyclohexane 
• 17264-54-9 sodium p-methylbenzoate 
• 60940-94-5 cis-4-methyl-cyclohexane-carboxylic acid-⁽¹⁾-amide 
• 7647-01-0 hydrogenchloride 
• 27332-44-1 1,3,5-cycloheptatriene-1-carboxylic acid 
• 589-91-3 p-methylcyclohexanol 
• 1879-06-7 4-acetyl-1-methylcyclohexane 

Downstream Products

• 934-67-8 trans-4-methylcyclohexanecarboxylic acid 
• 3937-48-2 (cis-4-Methyl-cyclohexyl)-methanol 
• 25244-23-9 cis-4-methyl-1-(ethoxycarbonyl)cyclohexane 
• 60940-94-5 cis-4-methyl-cyclohexane-carboxylic acid-⁽¹⁾-amide 
• 93007-36-4 cis-4-methyl-cyclohexane-carboxylic acid-⁽¹⁾-(4-bromo-phenacyl ester) 
• 3937-49-3 (trans-4-methylcyclohexyl)methanol 
• 55930-23-9 trans-4-methylcyclohexanecarbonyl chloride 
• 591-47-9 4-methylcyclohexene 
• 7731-29-5 trans-4-methylcyclohexan-1-ol 
• 589-92-4 1-methylcyclohexan-4-one 
• 624715-22-6 2,4,6-trimethylphenyl trans-4-cycolhexanecarboxylate 
• 195138-23-9 benzyl 2-acetyl-4-(trans-4-methylcyclohexyl)-4-oxobutyrate 
• 859204-10-7 methyl 2-{isopropyl[(trans-4-methylcyclohexyl)carbonyl]amino}thiophene-3-carboxylate 
• 859204-41-4 tert-butyl 4-[5-{isopropyl[(trans-4-methylcyclohexyl)carbonyl]amino}-4-(methoxycarbonyl)-2-thienyl]piperidine-1-carboxylate 

Relevant articles and documents

Electrocatalytic hydrogenation of benzoic acids in a proton-exchange membrane reactor

The highly efficient chemoselective electrocatalytic hydrogenation of benzoic acids (BAs) to cyclohexanecarboxylic acids (CCAs) was carried out in a proton-exchange membrane reactor under mild conditions without hydrogenation of the carboxyl group. Among the investigated catalysts, the PtRu alloy catalyst was found to be the most suitable for achieving high current efficiencies for production of CCAs. An electrochemical spillover mechanism on the PtRu alloy catalyst was also proposed.

NOVEL COMPOUNDS

Novel rapamycin analogues and methods for their production with FKBP and/or MIP inhibitory activity with reduced mTOR inhibitory activity with therapeutic potential e.g. as bacterial virulence inhibitors.

Epimerization of 2- or 4- substituted cyclohexanecarboxylic acids

The present invention relates to a new method for obtaining a purity of about 93% to 100% of the trans form of 2- or 4-substituted cyclohexanecarboxylic acid or reactive derivatives thereof from the cis form or a mixture of the cis and trans forms by a single step, particularly, to a method for obtaining a purity of substantially 100% of the trans form of 4-substituted cyclohexanecarboxylic acid.