41703-33-7

Basic information

• Product Name: (S)-2,2,6-Trimethyl-4-(tetrahydro-pyran-2-yloxy)-cyclohexanone
• CAS NO: 41703-33-7
• Molecular Weight: 240.343
• Mol File: 41703-33-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2,2,6-Trimethyl-4-(tetrahydro-pyran-2-yloxy)-cyclohexanone(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2,2,6-Trimethyl-4-(tetrahydro-pyran-2-yloxy)-cyclohexanone(41703-33-7)
• EPA Substance Registry System: (S)-2,2,6-Trimethyl-4-(tetrahydro-pyran-2-yloxy)-cyclohexanone(41703-33-7)

Safety Data

• Hazardous Substances Data: 41703-33-7(Hazardous Substances Data)

Upstream product

• 76451-81-5 (+/-)-2,2-Dimethyl-4,4-ethylenedioxy-1-cyclohexanol 
• 123214-39-1 (+/-)-4-Hydroxy-2,2-dimethyl-1-cyclohexanone 
• 131319-94-3 (-)-(S)-4-Hydroxy-2,2-dimethyl-1-cyclohexanone 
• 123196-48-5 (+/-)-2,2-Dimethyl-4-tetrahydropyranyloxy-1-cyclohexanone 
• 131206-75-2 3,3-Dimethyl-4,4-ethylenedioxy-1-cyclohexanone 
• 1193-47-1 2,2-dimethyl-cyclohexanone 
• 110-87-2 3,4-dihydro-2H-pyran 
• 123196-48-5 (S)-2,2-Dimethyl-4-(tetrahydro-pyran-2-yloxy)-cyclohexanone 
• 74-88-4 methyl iodide 

Downstream Products

• 152203-18-4 (+)-1-(1E,3Z)-(1S,4R,6S)-1-(4-carbomethoxy-3-methyl-1,3-butadienyl)-2,2,6-trimethylcyclohexan-1,4-diol 
• 76686-09-4 (+)-(R)-4-Hydroxy-2,6,6-trimethyl-2-cyclohexen-1-one 

Relevant articles and documents

Enzymatic Preparation of Chiral 4-Hydroxy-2,2-dimethyl-1-cyclohexanone as a Chiral Building Block

(S)-4-Hydroxy-2,2-dimethyl-1-cyclohexanone (1a) was prepared by two enzymatic methods. 1,4-Cyclohexanediol was converted to monoacetal (11) via (+/-)-1a.Enzymatic reduction of 11 by baker's yeast gave (S)-1 of almost 100 percent e.e.Direct hydroxylation of 2,2-dimethyl-1-cyclohexanone (14) by P-450 camphor monooxygenase of the cloned genes of Pseudomonas putida PpG1 gave (S)-1a of almost 100 percent e.e., too.According to Mitsunobu's method, SN-2 inversion of (S)-1 gave (R)-1.