41834-62-2

Basic information

• Product Name: 2-(benzylsulfanyl)-4,5-dihydro-1,3-thiazole
• Synonyms: 2-(Benzylsulfanyl)-4,5-dihydro-1,3-thiazole; thiazole, 4,5-dihydro-2-[(phenylmethyl)thio]-
• CAS NO: 41834-62-2
• Molecular Formula: C₁₀H₁₁NS₂
• Molecular Weight: 209.331
• Mol File: 41834-62-2.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 340.5°C at 760 mmHg
• Flash Point: 159.7°C
• Density: 1.22g/cm³
• Vapor Pressure: 0.000169mmHg at 25°C
• Refractive Index: 1.651
• CAS DataBase Reference: 2-(benzylsulfanyl)-4,5-dihydro-1,3-thiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(benzylsulfanyl)-4,5-dihydro-1,3-thiazole(41834-62-2)
• EPA Substance Registry System: 2-(benzylsulfanyl)-4,5-dihydro-1,3-thiazole(41834-62-2)

Safety Data

• Hazardous Substances Data: 41834-62-2(Hazardous Substances Data)

Usage

Thiazole derivative

A derivative of thiazole This compound is based on the thiazole structure, which is a five-membered heterocyclic ring system containing one nitrogen atom and one sulfur atom.

Benzylsulfanyl group attachment

Attached to the second carbon atom A benzylsulfanyl group (C6H5CH2S-) is attached to the second carbon atom of the thiazole ring, which influences the compound's properties and reactivity.

Potential biological activities

Antimicrobial and antiparasitic properties Studies have been conducted on this compound to explore its possible applications in treating infections and parasitic infestations due to its ability to inhibit the growth of microorganisms and parasites.

Building block in organic synthesis

Used for preparing pharmaceuticals and agrochemicals 2-(benzylsulfanyl)-4,5-dihydro-1,3-thiazole serves as an intermediate compound in the synthesis of various pharmaceutical and agrochemical products, making it a valuable component in these industries.

Corrosion inhibitor potential

Investigated for use on metal surfaces This compound has been researched for its possible application as a corrosion inhibitor, which could protect metal surfaces from degradation and extend their lifespan.

Upstream product

• 100-44-7 benzyl chloride 
• 96-53-7 2-mercaptothiazoline 
• 134469-06-0 thiazolidine-2-thione 
• 100-39-0 benzyl bromide 
• 412308-18-0 (2-hydroxy-ethyl)-dithiocarbamic acid benzyl ester 

Downstream Products

• 49631-00-7 cyano-thiazolidin-2-ylidene-thioacetic acid S-benzyl ester 
• 30760-56-6 2-Benzoylaminoethylbenzyldithiocarbonat 
• 50668-02-5 2-(1-phenyl-ethylsulfanyl)-4,5-dihydro-thiazole 
• 30760-51-1 3-(4-nitro-benzyl)-thiazolidine-2-thione 
• 49630-93-5 (3-acetyl-thiazolidin-2-ylidene)-cyano-thioacetic acid S-benzyl ester 
• 31285-73-1 3-benzoyl-2-benzylsulfanyl-4,5-dihydro-thiazolium; bromide 

Relevant articles and documents

Simple and convenient synthesis of 2-(substituted-benzylsulfanyl)-4,5- dihydrothiazoles and their antimicrobial activity studies

A simple and convenient procedure for the preparation of 2-(substitutedbenzylsulfanyl)-4,5-dihydrothiazoles by the reaction of 4,5-dihydro-thiazole-2-thiol and benzyl bromides in acetone/K2CO 3 condition has been reported.

Synthesis method and application of 3-benzyl-1,3-thiazolidine-2-thione

The invention provides a synthesis method of 3-benzyl-1,3-thiazolidine-2-thione. The synthesis method comprises the following step of performing reaction on 1,3-thiazolidine-2-thione, an alkaline reagent and benzyl halide in a solvent to obtain the 3-benzyl-1,3-thiazolidine-2-thione. According to the synthesis method, an optimization condition of synthesizing the 3-benzyl-1,3-thiazolidine-2-thionethrough exploration, the yield of the 3-benzyl-1,3-thiazolidine-2-thione is 67.8 percent, and the purity reaches up to 99.99 percent. Further, when the 3-benzyl-1,3-thiazolidine-2-thione is synthesized with the method provided by the invention, 2-benzylthio-1,3-thiazolidine as an isomer can also be produced, and the two compounds both have higher activity in a herbicide and an insecticide. In addition, the invention also provides application of the 3-benzyl-1,3-thiazolidine-2-thione in the herbicide and the insecticide.

Reaction of 2-thiazolidinethione with halohydrocarbon: Synthesis of novel N-alkylated 2-thiazolidinethione and S-alkylated thiazoline derivatives

Reaction of 2-thiazolidinethione with halohydrocarbon in ethanol gave a series of N-alkylated 2-thiazolidinethione and S-alkylated thiazoline derivatives in excellent yields. The reaction was carried out under mild conditions using NaOH as a base and it did not require protection from air.