41873-66-9Relevant academic research and scientific papers
6-exo-trig Michael addition-lactonizations for catalytic enantioselective chromenone synthesis
Neyyappadath, Rifahath M.,Cordes, David B.,Slawin, Alexandra M. Z.,Smith, Andrew D.
, p. 2555 - 2558 (2017/03/09)
The catalytic enantioselective 6-exo-trig Michael addition-lactonization of enone-acid substrates to form cis-chromenones with high diastereo- and enantiocontrol was developed using the commercially available isothiourea tetramisole. An acidic workup prov
Isoaurones: synthesis and stereochemical assignments of geometrical isomers
Venkateswarlu, Somepalli,Panchagnula, Gopala K.,Guraiah, Mothukuri Bala,Subbaraju, Gottumukkala V.
, p. 9855 - 9860 (2007/10/03)
A series of isoaurones have been synthesized for the first time from substituted acetophenones via benzo-2(3H)-furanone in three steps. Geometrical isomers of the isoaurones were separated. The differences in the proton and carbon NMR spectra of the E- and Z-isoaurones afford a useful method for distinguishing between the two isomers. Marginalin, a metabolite of Dytiscus marginalis has been synthesized and the spectral data of the synthetic E-isomer were in good agreement with those of the natural product. The antioxidant activity of isoaurones was determined by superoxide free radical (NBT) method and isoaurones 12 and 13 displayed excellent antioxidant activity.
Spherands with Functional Groups in the Outer Sphere: Synthesis from Modified 1,1':3',1''-Terphenyls
Dijkstra, Pieter J.,Boerrigter, Jos C. Olde,Steen, Bart J. van,Hertog, Herman J. den,Reinhoudt, David N.
, p. 1660 - 1661 (2007/10/02)
Two spherands (1a,c), functionalized in the outer sphere, have been synthesized by oxidative coupling of the dianions of terphenyls; these terphenyls are obtained by aldol condensation of 1,3-diarylpropanones with nitromalonaldehyde.
