3007-53-2Relevant articles and documents
NMR Relaxation in Isotropic Surfactant Systems. A 2H, 13C, and 14N NMR Study of the Micellar (L1) and Cubic (I1) Phases in the Dodecyltrimethylammonium Chloride/Water System
Soderman, Olle,Walderhaug, Harald,Henriksson, Ulf,Stilbs, Peter
, p. 3693 - 3701 (1985)
A 2H, 13C, 14N NMR spin relaxation study of micellar solutions and cubic liquid-crystalline phases formed in the two-component system dodecyltrimethylammonium chloride (DOTAC)1/water is presented.In particular, based on multifield 2H NMR relaxation data, covering the frequency range 1.8-55.2 MHz, it is concluded that the NMR spin relaxation in ordinary micelles is determined by the fast local motion (trans-gauche isomerization) of the CD2 segment of the hydrocarbon chains of the monomers and the rotational tumbling of the micelles and diffusion of monomers over the (curved) micellar surface.There is no need to invoke other motions to explain the spin relaxation over a wide frequency range for he micellar case.For the cubic phase at high water content, the relaxation data are interpreted in favor of a novel structure, recently presented for this phase.The data also indicate that the interior or the amphiphilic aggregates is liquidlike and that the orientational order imposed by the hydrophobic-hydrophylic interface depends only weakly on the geometry of aggregates.
Ni-Catalyzed Α-Alkylation of Unactivated Amides and Esters with Alcohols by Hydrogen Auto-Transfer Strategy
Midya, Siba P.,Rana, Jagannath,Pitchaimani, Jayaraman,Nandakumar, Avanashiappan,Madhu, Vedichi,Balaraman, Ekambaram
, p. 3911 - 3916 (2018/11/23)
A transition-metal-catalyzed borrowing hydrogen/hydrogen auto-transfer strategy allows the utilization of feedstock alcohols as an alkylating partner, which avoids the formation of stoichiometric salt waste and enables a direct and benign approach for the construction of C-N and C?C bonds. In this study, a nickel-catalyzed α-alkylation of unactivated amides and ester (tert-butyl acetate) is carried out by using primary alcohols under mild conditions. This C?C bond-forming reaction is catalyzed by a new, molecularly defined nickel(II) NNN-pincer complex (0.1–1 mol %) and proceeds through hydrogen auto-transfer, thereby releasing water as the sole byproduct. In addition, N-alkylation of cyclic amides under Ni-catalytic conditions is demonstrated.
Pd(PPh3)4 catalyzed amide compound synthesis method
-
Paragraph 0086; 0087; 0088; 0089; 0090, (2017/12/27)
The invention relates to a Pd(PPh3)4 catalyzed amide compound synthesis method. The synthesis method takes carboxylic acid as the substrate, and adopts N-substituted formamide as the amine source to synthesize an amide compound under the catalysis of Pd(PPh3)4. The method is widely applicable to substrates with different functional groups. The amide compound efficiently constructed by the invention is an important skeleton of many organic molecules, drugs, peptides, bioactive molecules and natural products. The synthesis method provided by the invention provides a widely applicable preparation method for synthesis of the compounds.
