41927-37-1

Upstream product

• 100-52-7 benzaldehyde 
• 871694-12-1 (1-vinyloxy-but-3-enyl)-benzene 
• 110891-00-4 (αR^*)-α-((1R^*, 2R^*)-2-methyl-1-((S^*)-phenylsulfinyl)butyl)benzyl alcohol 
• 110891-00-4 (αR^*)-α-((1S^*, 2R^*)-2-methyl-1-((S^*)-phenylsulfinyl)butyl)benzyl alcohol 
• 110891-02-6 (+/-)-(αR^*)-α-((1S^*,2R^*)-2-methyl-1-((S^*)-(1-methylimidazol-2-yl)sulfinyl)butyl)benzyl alcohol 
• 110891-05-9 1-Methyl-4-((R)-(R)-2-methyl-butane-1-sulfinyl)-benzene 
• 110891-00-4 (αS^*)-α-((1R^*, 2R^*)-2-methyl-1-((S^*)-phenylsulfinyl)butyl)benzyl alcohol 
• 110891-00-4 (αS^*)-α-((1S^*, 2R^*)-2-methyl-1-((S^*)-phenylsulfinyl)butyl)benzyl alcohol 
• 110891-02-6 (+/-)-(α^*)-α-((1R^*,2R^*)-2-methyl-1-((R^*)-1-methylimidazol-2-yl)sulfinyl)butylbenzyl alcohol 
• 110891-01-5 1-Methyl-2-((R)-(R)-2-methyl-butane-1-sulfinyl)-1H-imidazole 
• 110890-99-8 ((R)-(S)-2-Methyl-butane-1-sulfinyl)-benzene 
• 106345-46-4 (+)-(αS)-α-((1S,2R)-2-methyl-1-((R)-p-tolylsulfinyl)-butyl)benzyl alcohol 
• 110891-01-5 1-Methyl-2-((R)-(S)-2-methyl-butane-1-sulfinyl)-1H-imidazole 
• 106345-46-4 (-)-(αR)-α-((1R, 2R)-2-methyl-1-((R)-p-tolylsulfinyl)-butyl)benzyl alcohol 

Relevant academic research and scientific papers

Zirconocene-catalyzed reactions of alkenyl-substituted enol ethers

(Chemical Equation Presented) A straightforward approach: An unprecedented zirconocene-catalyzed isomerization-magnesation reaction of readily available alkene-substituted enol ethers allows the direct synthesis of functionalized Grignard reagents. Cp = c

Regioselective Vinylation of Remote Unactivated C(sp3)?H Bonds: Access to Complex Fluoroalkylated Alkenes

Regioselective incorporation of a particular functional group into aliphatic sites by direct activation of unreactive C?H bonds is of great synthetic value. Despite advances in radical-mediated functionalization of C(sp3)?H bonds by a hydrogen-atom transfer process, the site-selective vinylation of remote C(sp3)?H bonds still remains underexplored. Reported herein is a new protocol for the regioselective vinylation of unactivated C(sp3)?H bonds. The remote C(sp3)?H activation is promoted by a C-centered radical instead of the commonly used N and O radicals. The reaction possesses high product diversity and synthetic efficiency, furnishing a plethora of synthetically valuable E alkenes bearing tri-/di-/mono-fluoromethyl and perfluoroalkyl groups.

STUDIES OF STEREOCHEMICAL CONTROL USING α-LITHIOSULFINYL CARBANIONS

The stereoselectivity in reactions of α-lithiosulfinyl carbanions with aldehydes has been unambiguously established.Steric effects and intramolecular chelation of the associated cation are important factors contributing to the observed outcome.