41968-39-2Relevant academic research and scientific papers
SYNTHESIS OF FUNCTIONALISED CEPHALOSPORINS. DIPHENYLMETHYL(1S,6R,7S)-3-BROMOMETHYL-7-FORMAMIDO-7-METHOXYCEPH-3-EM-4-CARBOXYLATE-1-OXIDE : A USEFUL INTERMEDIATE IN THE PREPARATION OF 7α-METHOXYCEPHALOSPORINS
Biggadike, K.,Humber, D. C.,Laundon, B.,Long, A. G.,Ramsay, M. V. J.
, p. 2025 - 2032 (2007/10/02)
The N-formamido cephalosporins 4a and 4b undergo direct methoxylation at the 7α-position to give the 7α-methoxy derivatives 5a and 5b.These were converted to other 7β-acylamido compounds by the sequence : oxidation, deformylation, acylation and reduction.
