42014-54-0

Upstream product

• 6066-82-6 1-hydroxy-pyrrolidine-2,5-dione 
• 4224-70-8 6-bromohexanoic acid 
• 4286-55-9 1-bromo-6-hexanol 

Downstream Products

• 1151515-41-1 C₃₇H₄₄N₃O₄S₂⁽¹⁺⁾*Br^(1-) 
• 1242242-37-0 C₄₆H₆₂N₂O₄PS₂⁽¹⁺⁾*Br^(1-) 
• 4224-70-8 6-bromohexanoic acid 

Relevant academic research and scientific papers

IBX-mediated oxidation of primary alcohols and aldehydes to form carboxylic acids

Under mild conditions and without the use of toxic metals, the oxidation of primary alcohols and aldehydes to the corresponding carboxylic acids with 1-hydroxy-1,2-benziodoxole-3(1H)-one-1-oxide (IBX) proceeds in the presence of 1-hydroxypyridine or N-hydroxysuccinimide (see scheme). The reaction tolerates a wide variety of functional groups.

Labeling reagents and labeled targets, target labeling processes and other processes for using same in nucleic acid determinations and analyses

This invention provides for labeling reagents, labeled targets and processes for preparing labeling reagents. The labeling reagents can take the form of cyanine dyes, xanthene dyes, porphyrin dyes, coumarin dyes or composite dyes. These labeling reagents are useful for labeling probes or targets, including nucleic acids and proteins. These reagents can be usefully applied to protein and nucleic acid probe based assays. They are also applicable to real-time detection processes.