4203-26-3Relevant academic research and scientific papers
Synthesis and evaluation of heteroaryl-ketone derivatives as a novel class of VEGFR-2 inhibitors
Piatnitski Chekler, Eugene L.,Katoch-Rouse, Reeti,Kiselyov, Alexander S.,Sherman, Dan,Ouyang, Xiaohu,Kim, Ki,Wang, Ying,Hadari, Yaron R.,Doody, Jacqueline F.
supporting information; experimental part, p. 4344 - 4347 (2009/04/06)
We have discovered novel inhibitors of VEGFR-2 kinase with low nanomolar potency in both enzymatic and cell-based assays. Active series are heteroaryl-ketone compounds containing a central aromatic ring with either an indazolyl or indolyl keto group in th
HETEROARYLAMINO-PHENYLKETONE DERIVATIVES AND THEIR USE AS KINASE INHIBITORS
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Page 33, (2010/02/10)
The present invention relates to compounds that inhibit VEGF receptor tyrosine kinases, especially KDR, pharmaceutical compositions that contain such compounds, methods of treating VEGF receptor kinase-dependent diseases and conditions in mammals using such compounds and composition and methods for their manufacture.
Photochemistry of 2-(methoxycarbonyl)phenyl azide studied by matrix-isolation spectroscopy. A new slippery energy surface for phenylnitrene
Tomioka, Hideo,Ichikawa, Naoki,Komatsu, Kazunori
, p. 8621 - 8626 (2007/10/02)
Broad-band irradiation (λ > 350 nm) of 2-(methoxycarbonyl)phenyl azide (1) in Ar at 10 K monitored by IR and UV-vis spectroscopy resulted in the formation of at least five major products, all of which were shown to be photointerconvertible under these con
