42074-16-8

Usage

Uses

Used in Pharmaceutical Industry:
N-BENZYL-N-(2-CHLOROETHYL)AMINE is used as a chemical intermediate for the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents.
Used in Organic Chemistry:
N-BENZYL-N-(2-CHLOROETHYL)AMINE is used as a versatile building block in organic chemistry for the manufacturing of a wide range of chemicals and materials, showcasing its importance in the creation of diverse chemical compounds.
Used in Chemical Manufacturing:
N-BENZYL-N-(2-CHLOROETHYL)AMINE is utilized in the production of various chemicals and materials, highlighting its role as a key component in the chemical industry.
Safety Note:
It is important to handle N-BENZYL-N-(2-CHLOROETHYL)AMINE with care, as it is known to be a skin and eye irritant, requiring proper safety measures during its use and storage.

Upstream product

• 2510-33-0 N-benzyl-2-oxazolidinone 
• 100-46-9 benzylamine 
• 107-07-3 2-chloro-ethanol 
• 104-63-2 N-Benzylethanolamine 
• 2564-06-9 N-benzyl-2-chloroacetamide 
• 870-24-6 2-chloroethanamine hydrochloride 
• 100-52-7 benzaldehyde 

Downstream Products

• 82462-01-9 N¹-benzyl-N²-decylethane-1,2-diamine 
• 263719-86-4 N²-BOC-N⁵-benzyl-1,2,5-thiadiazolidine 1,1-dioxide 
• 1158255-34-5 N-(phenylmethyl)-1H-pyrrole-1-ethanamine 

Relevant academic research and scientific papers

Preparation method of chiral morpholine compound

The invention provides a preparation method of a chiral morpholine compound. With chiral ethylene oxide as a raw material, the preparation method comprises the steps of ring opening, cyclization and deprotection reaction to obtain the chiral 2-substituted morpholine compound. The preparation process is simple and environmentally friendly, has mild reaction conditions, is free of irritation or allergens, has higher total yield and good safety and is suitable for industrial amplification.

New pseudonucleosides containing chiral oxazolidin-2-ones and Cyclosulfamides as aglycones: Synthesis and antiviral evaluation

A series of chiral cyclosulfamides and oxazolidinon-2-ones have been synthesized starting from aminoacids. Regioselective substitution of these pseudopyrimidic heterocyles was carried out under Mitsunobu conditions. Best substitution results were obtained by preliminary deprotection of cyclosulfamides and their condensation with β -D-ribofuranose. Chiral oxazolidin-2-ones were coupled directly with D-ribofuranose. All compounds were tested against HSV-2, VV and SV viruses. Two compounds 6b and 6e showed significant activities against HSV-type 1. Copyright Taylor & Francis Group, LLC.

Sodium borohydride-boron trifluoride ethereate, a convenient and efficient reagent for the reduction of amides

Sodium borohydride-boron trifluoride ethereate has been employed as a reducing agent for the conversion of amides into amines, the reducing species being diborane generated in situ.This method successfully reduces primary, secondary and tertiary amides, lactams and chiral diketopiperazines, in moderate to high yields.An unusual ring cleavage is observed in the reduction of the pyrroloquinazolin-1-one (7a) resulting in the formation of benz-1,6-diazonine (7b).

β-Lactam compounds

A compound of formula (I) or a pharmaceutically acceptable salt or in vivo hydrolysable ester thereof: STR1 wherein R represents an alkyl or aralkyl group, substituted on an alkyl carbon atom other than that adjacent to --NH-- group, with one or more functional groups selected from halogen, non-aromatic heterocyclyl linked through carbon, aromatic heterocyclyl, nitro, oxo, --OR1, SR1 --P(O)R2 R3, --NR4 R5, =NR6, or a sulphur linked organic radical, wherein R1, R2, R3, R4, R5 and R6 are various organic radicals. Processes for the preparation of these compounds and pharmaceutical compositions containing them are also disclosed.