4210-10-0Relevant academic research and scientific papers
K3PO4-catalyzed one-pot synthesis of β-amino ketones
Movassagh, Barahman,Khosousi, Sakineh
, p. 1503 - 1506 (2013/02/21)
A new strategy which uses cheap K3PO4 as a very effective catalyst has been developed for synthesis of β-amino ketones by one-pot reaction of an aryl aldehyde, acetophenone derivative, and amine in EtOH at room temperature. Springer-Verlag 2012.
SnCl45H2O-catalyzed synthesis of β-amino carbonyl compounds via a direct Mannich-type reaction
Wang, Min,Song, Zhiguo,Liang, Yan
experimental part, p. 1 - 6 (2011/12/22)
An efficient three-component, one-pot synthesis of β-amino carbonyl compounds from aromatic ketones, aromatic aldehydes, and aromatic amines using tin tetrachloride at room temperature in ethanol is described. The advantages of the new method are good yields (62-96%), simple workup, and inexpensive catalyst. Copyright Taylor & Francis Group, LLC.
Aluminium nitrate as an efficient and reusable catalyst for the three components one-pot Mannich reaction: Synthesis of β-amino carbonyl compounds
Wang, Min,Liang, Yan,Song, Zhiguo
supporting information; experimental part, p. 1653 - 1656 (2011/02/21)
Three components one-pot Mannich reaction of aromatic ketones, aromatic aldehydes and aromatic amines has been efficiently catalysed by recyclable aluminium nitrate at ambient temperature to give various β-amino carbonyl compounds in high yields. By simple phase separation, aluminium nitrate could be recycled several times without distinct loss of activity.
Non-Steroidal Androgen Receptor Modulators, Preparation Process, Pharmaceutical Composition and Use Thereof
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Page/Page column 7, (2009/01/20)
Non-steroidal androgen receptor modulating compounds of the general formula (I), their pharmaceutically acceptable salts, preparation process and pharmaceutically compositions containing the said compounds are disclosed. Such compounds of the general formula (I) or their pharmaceutically acceptable salts can be used for preparing non-steroidal medicines to treat and/or prevent conditions or diseases such as prostatic hyperplasia, prostate cancer, hirsutism, severe hormone-dependent alopecia or acne, etc. as a result of androgen receptor antagonistic activities.
NONSTEROIC ANDROGEN ACCEPTOR REGULATORS, PREPARATION PROCESS, PHARMACEUTICAL COMPOSITION AND USE THEREOF
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Page/Page column 11, (2010/11/30)
Nons-teroidal androgen receptor modulating compounds of the general formula (I), their pharmaceutically acceptable salts, preparation process and pharmaceutically compositions containing the said compounds are disclosed. Such compounds of the general formula (I) or their pharmaceutically acceptable salts can be used for preparing non-steroidal medicines to treat and/or prevent condictions or diseases such as prostatic hyperplasia, prostate cancer, hirsutism, severe hormone-dependent alopecia or acne, etc. as a result of androgen receptor antagonistic activities.
