42103-84-4Relevant academic research and scientific papers
Temperature-controlled synthesis of N-acyl anthranilamides and quinazoline-4ones via Pd-catalysed cascade consisting of isocyanide insertion
Khan, Irfan,Singh, Jaybir,Khan, Imran,Dutt, Sunil,Khan, Shahnawaz,Tyagi, Vikas
, p. 279 - 291 (2019/08/12)
A one step synthesis of functionlized N-acyl anthranilamide via Pd-catalyzed carboxamidation of o-halo substituted N-phenylamide consisting of isocyanide insertion followed by oxidation of the imine intermediate has been achived successfully. Furthermore,
Comparative Catalytic Activity of Group 9 [CpMIII] Complexes: Cobalt-Catalyzed C-H Amidation of Arenes with Dioxazolones as Amidating Reagents
Park, Juhyeon,Chang, Sukbok
, p. 14103 - 14107 (2016/01/25)
A procedure for the [CpCoIII]-catalyzed direct C-H amidation of arenes with dioxazolone has been developed. This reaction proceeds under straightforward and mild conditions with a broad range of substrates, including anilides. A comparative study on the catalytic activity of Group 9 [{CpMCl2}2] complexes revealed the unique efficiency of the cobalt catalyst. Pick of the bunch: A variety of arenes, including anilides, underwent direct C-H amidation with dioxazolones in the presence of a cobalt catalyst with a Cp? ligand under mild and straightforward reaction conditions (see scheme; Piv=pivaloyl). A comparative study of Group 9 [CpMIII] complexes revealed the unique ability of the cobalt catalyst to promote this transformation efficiently.
Microwave-assisted one-pot synthesis of 2,3-disubstituted 3H-quinazolin-4-ones
Liu, Ji-Feng,Lee, Jaekyoo,Dalton, Audra M.,Bi, Grace,Yu, Libing,Baldino, Carmen M.,McElory, Eric,Brown, Matt
, p. 1241 - 1244 (2007/10/03)
A practical synthesis of 2,3-disubstituted 3H-quinazolin-4-ones 1 with broad chemistry scope is described. The key step is the microwave promoted one-pot, two-step reaction sequence combining anthranilic acids, carboxylic acids, and amines providing efficient access to this important class of heterocycles.
