4212-65-1

Basic information

• Product Name: (2,3,5-trihydroxy-4-oxo-pentoxy)phosphonic acid
• Synonyms: Xylulose 5-phosphate;D-xylulose 5-phosphate
• CAS NO: 4212-65-1
• Molecular Formula: C₅H₁₁O₈P
• Molecular Weight: 0
• Mol File: 4212-65-1.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 620.3°C at 760 mmHg
• Flash Point: 329°C
• Appearance: /
• Density: 1.812g/cm³
• Vapor Pressure: 5.5E-18mmHg at 25°C
• Refractive Index: 1.566
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: Methanol (Slightly), Water
• Stability: Unstable in Solution
• CAS DataBase Reference: (2,3,5-trihydroxy-4-oxo-pentoxy)phosphonic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (2,3,5-trihydroxy-4-oxo-pentoxy)phosphonic acid(4212-65-1)
• EPA Substance Registry System: (2,3,5-trihydroxy-4-oxo-pentoxy)phosphonic acid(4212-65-1)

Safety Data

• Hazardous Substances Data: 4212-65-1(Hazardous Substances Data)

Usage

Uses

D-Xylulose 5-Phosphate, is a metabolite present in the hexose monophosphate pathway that activates the protein phosphatase 2A.

Definition

ChEBI: The D-enantiomer of xylulose 5-phosphate.

InChI:InChI=1/C5H11O8P/c6-1-3(7)5(9)4(8)2-13-14(10,11)12/h4-6,8-9H,1-2H2,(H2,10,11,12)/t4-,5-/m1/s1

Upstream product

• 532-20-7 D-Ribose 
• 58-86-6 D-xylose 
• 551-85-9 Ribulose-5-phosphate 
• 1113-60-6 3-hydroxy-2-oxopropionic acid 
• 591-57-1 D-glyceraldehyde-3-phosphate 

Downstream Products

• 591-57-1 D-glyceraldehyde-3-phosphate 
• 590-54-5 acetylphosphoric acid 
• 3019-74-7 sedoheptulose 

Relevant articles and documents

Chemical Synthesis of Ketopentose-5-phosphates

A chemical synthesis of ketopentose-5-phosphates that are involved in the pentose phosphate pathway has been developed. The ketopentose phosphates, d-ribulose-5-phosphate and d-xylulose-5-phosphate, were prepared in five steps starting from known intermed

Synthesis of arabinitol 1-phosphate and its use for characterization of arabinitol-phosphate dehydrogenase

D-Arabinitol 1-phosphate (Ara-ol1-P), a substrate for d-arabinitol- phosphate dehydrogenase (APDH), was chemically synthesized from d-arabinonic acid in five steps (O-acetylation, chlorination, reduction, phosphorylation, and de-O-acetylation). Ara-ol1-P was used as a substrate for the characterization of APDH from Bacillus halodurans. APDH converts Ara-ol1-P to xylulose 5-phosphate in the oxidative reaction; both NAD+ and NADP+ were accepted as co-factors. Kinetic parameters for the oxidative and reductive reactions are consistent with a ternary complex mechanism.

UTILIZATION OF ENZYMES IN ORGANIC CHEMISTRY : TRANSKETOLASE CATALYZED SYNTHESIS OF KETOSES

Substrate specificity of bakers' yeast transketolase has been studied: the enzyme appears to be enantioselective towards the acceptor aldehyde.L-erythrulose, D-xylulose and 5-deoxy-D-xylulose have been synthesized by spinach transketolase catalyzed condensation of hydroxypyruvate and the corresponding aldehyde.