D-Xylulose 5-phosphate

Base Information

• Chemical Name: D-Xylulose 5-phosphate
• CAS No.: 4212-65-1
• Molecular Formula: C5H11O8P
• Molecular Weight: 230.111
• UNII: 6MF87847MR
• DSSTox Substance ID: DTXSID60863330
• Nikkaji Number: J652.282C
• Wikipedia: Xylulose_5-phosphate
• Wikidata: Q27094888
• Metabolomics Workbench ID: 37475
• Mol file: 4212-65-1.mol

Synonyms:D-xylulose-5-phosphate;xylulose-5-phosphate;xylulose-5-phosphate, (D)-isomer

Chemical Property of D-Xylulose 5-phosphate

Chemical Property:

• Vapor Pressure: 5.5E-18mmHg at 25°C
• Boiling Point: 620.3°C at 760 mmHg
• Flash Point: 329°C
• Density: 1.812g/cm³
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility.: Methanol (Slightly), Water
• XLogP3: -3.7
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 6
• Exact Mass: 230.01915430
• Heavy Atom Count: 14
• Complexity: 234

Purity/Quality:

D-Xylulose-5-phosphate 88.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(C(C(=O)CO)O)O)OP(=O)(O)O
• Isomeric SMILES: C([C@H]([C@@H](C(=O)CO)O)O)OP(=O)(O)O
• Uses: D-Xylulose 5-Phosphate, is a metabolite present in the hexose monophosphate pathway that activates the protein phosphatase 2A.

Technology Process of D-Xylulose 5-phosphate

There total 7 articles about D-Xylulose 5-phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

1,3,4-tri-O-benzyl-5-O-dibenzyl phosphate-D-threo pentulose → D-xylulose 5-phosphate (4212-65-1,2922-69-2,4151-19-3,60802-29-1)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In ethanol; at 20 ℃; for 24h; under 1810.07 Torr;

DOI:10.1002/ejoc.201601639

Reference yield: 91.0%

D-xylose (58-86-6) → D-xylulose 5-phosphate (4212-65-1,2922-69-2,4151-19-3,60802-29-1)

Guidance literature:

With D-xylulose kinase; Escherichia coli D-xylose isomerase; ATP; sodium hydroxide; pH=7.5; Enzymatic reaction;

DOI:10.1021/acscatal.5b02234

Reference yield:

3-hydroxy-2-oxopropionic acid (1113-60-6) + D-glyceraldehyde-3-phosphate (591-57-1) → D-xylulose 5-phosphate (4212-65-1,2922-69-2,4151-19-3,60802-29-1)

Guidance literature:

With thiamine pyrophosphate; magnesium chloride; S_.cerevisiae transketolase; 0.1 M glycylglycine buffer, pH=7.6;

DOI:10.1016/S0040-4039(00)96770-4

upstream raw materials:

3-hydroxy-2-oxopropionic acid

D-glyceraldehyde-3-phosphate

D-Ribose

Ribulose-5-phosphate

Downstream raw materials:

sedoheptulose

D-glyceraldehyde-3-phosphate

acetylphosphoric acid