42156-76-3

Upstream product

• 85-56-3 2-(4-chlorobenzoyl)benzoic acid 
• 108-90-7 chlorobenzene 
• 85-44-9 phthalic anhydride 
• 13450-37-8 o-(3-chloro-benzoyl)-benzoic acid 

Downstream Products

• 91148-60-6 6,12-bis(4-chlorophenyl)dibenzo[b,f][1,5]diazocine 
• 131-09-9 2-chloroanthracene-9,10-dione 
• 849723-43-9 N-{2-[1-(4-chlorophenyl)-1-hydroxy-3-oxo-1,3-dihydroisoindol-2-yl]ethyl}acetamide 
• 203791-84-8 2-(4-Chloro-benzoyl)-thiobenzoic acid S-phenyl ester 

Relevant academic research and scientific papers

Biomimetic Asymmetric Reduction of Tetrasubstituted Olefin 2,3-Disubstituted Inden-1-ones with Chiral and Regenerable NAD(P)H Model CYNAM

Because of the formidable development of the asymmetric reduction of tetrasubstituted olefins, an effective method is in urgent demand. Herein, through the biomimetic protocol of the coenzyme NAD(P)H, the reduction of tetrasubstituted olefin 2,3-substitut

A rapid and efficient access to diaryldibenzo[b,f][1,5]diazocines

2-Benzoylbenzoyl azides undergo facile cyclization under acidic conditions to give substituted dibenzo[b,f][1,5]-diazocines in good yields. This approach shortens the synthetic steps toward these compounds as compared with conventional methods. The mechanism of the diazocine synthesis is assumed to proceed by an unprecedented intermolecular [2 + 2] cyclization.

ISOINDOLIN-1-ONE DERIVATIVES

A compound of formula (1) or a prodrug and/or pharmaceutically acceptable salt thereof, wherein X is selected from O, N or S; R1 is selected from hydrogen, halo, hydroxy, substituted or unsubstituted alkyl, substituted or unsubstituted hydroxyalkyl, substituted or unsubstituted alkylamine, alkoxy, substituted or unsubstituted aryl or heteroaryl, and substituted or unsubstituted aralkyl or heteroaralkyl; R2 is selected from hydrogen, halo, hydroxy, substituted or unsubstituted alkyl, substituted or unsubstituted hydroxyalkyl substituted or unsubstituted alkylamine, alkoxy, substituted or unsubstituted aryl or heteroaryl, and substituted or unsubstituted aralkyl or heteroalkyl; R3 is selected from hydrogen, halo, hydroxy, substituted or unsubstituted alloy substituted or unsubstituted hydroxyalkyl, substituted or unsubstituted alkylamine alkoxy, substituted or unsubstituted aryl or heteroaryl, and substituted or unsubstituted aralkyl or heteroalkyl; and R4-R7, is used to represent groups R4, R5, R6 and R7 which are independently selected from H, OH, alkyl, alkoxy, alkylamine, hydroxyalkyl, halo, CF3, NH2, NO2, COOH, C=0.