42245-33-0

Upstream product

• 4720-29-0 3-(benzylamino)propan-1-ol 
• 6276-54-6 3-chloropropylamine hydrochloride 
• 100-52-7 benzaldehyde 

Downstream Products

• 13910-48-0 N-benzyl-1,3-diaminopropane 
• 98902-03-5 N-(3-benzylaminopropyl)benzamide 
• 95484-11-0 3,4-bis(benzyloxy)-α-acetophenone 
• 95484-12-1 1,2-bis(benzyloxy)-4-<1-hydroxy-2-ethyl>benzene 
• 95484-13-2 1,2-bis(benzyloxy)-4-<1-hydroxy-2-ethyl>benzene 
• 95484-15-4 N-(3-{Benzyl-[2-(3,4-bis-benzyloxy-phenyl)-2-hydroxy-ethyl]-amino}-propyl)-acetamide 
• 95484-14-3 1-(3-{Benzyl-[2-(3,4-bis-benzyloxy-phenyl)-2-hydroxy-ethyl]-amino}-propyl)-3-phenyl-urea 
• 95484-16-5 2-Acetylamino-N-(3-{benzyl-[2-(3,4-bis-benzyloxy-phenyl)-2-hydroxy-ethyl]-amino}-propyl)-acetamide 
• 389132-03-0 3-azido-N-benzylpropan-1-amine 
• 1352840-47-1 C₄₀H₄₇N₉O₂ 
• 729-19-1 1-benzyl-3-phenyl-4,5-dihydro-1H-pyrazole 

Relevant academic research and scientific papers

Dual PPAR-delta and PPAR-gamma agonists

The present invention relates to compositions and methods using for activating Peroxisomal Proliferator Activating Receptor (PPAR)-β/δ and/or PPAR-γ. In some embodiments, the present invention relates to compounds and methods of treating a disease or disorder associated with PPAR-β/δ and/or PPAR-γ. In some embodiments, present invention relates to compounds and methods of treating Alzheimer's disease, diabetes, and reduced cognition.

Fe(III)-Catalyzed Aerobic Intramolecular N-N Coupling of Aliphatic Azides with Amines

An Fe(III)-catalyzed intramolecular N-N coupling of aliphatic azidoamines that forms diverse five- and six-membered semisaturated diazoheterocycles using air as an oxidant is reported, providing an alternative to hydrazine-based methods. Mechanistic studies suggest that a N-radical induced intramolecular homolytic substitution (SH2) is involved in ring closure. The power of this N-N bond-forming method is also demonstrated by using it as the final step in a total synthesis of (-)-newbouldine.

A twin-axial hetero[7]rotaxane

Two in one: Two pseudorotaxanes can be combined to form a twin-axial hetero[7]rotaxane (see picture) by using the copper-catalyzed alkyne-azide "click" reaction. The synthetic route, in which twin-axial and single-axial rotaxanes are formed, combines self

Synthesis of substituted piperidines, indolizidines, quinolizidines, and pyrrolizidines via a cycloaddition strategy using acetylenic sulfones as alkene dipole equivalents

(equation presented) The conjugate additions of β- and γ-chloroamines to acetylenic sulfones afford enamine sulfones, which then undergo intramolecular alkylation to produce the corresponding cyclic enamines. This provides a convenient route to substitute