423115-90-6

Basic information

• Product Name: 1-Butanone, 1-(4-methoxyphenyl)-, oxime
• CAS NO: 423115-90-6
• Molecular Formula: C11H15NO2
• Molecular Weight: 193.246
• Mol File: 423115-90-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-Butanone, 1-(4-methoxyphenyl)-, oxime(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Butanone, 1-(4-methoxyphenyl)-, oxime(423115-90-6)
• EPA Substance Registry System: 1-Butanone, 1-(4-methoxyphenyl)-, oxime(423115-90-6)

Safety Data

• Hazardous Substances Data: 423115-90-6(Hazardous Substances Data)

Upstream product

• 4160-51-4 1-(4-methoxyphenyl)-1-butanone 

Downstream Products

• 5421-40-9 N-(4-methoxyphenyl)butyramide 
• 51089-97-5 1-(4-methoxy-phenyl)-butylamine 

Relevant articles and documents

Copper-Catalyzed Aza-Sonogashira Cross-Coupling To Form Ynimines: Development and Application to the Synthesis of Heterocycles

Nitrogen-substituted alkynes, such as ynamines and ynamides, are versatile synthetic building blocks. Ynimines bearing additional nucleophilic and electrophilic centers relative to ynamines and ynamides are expected to have high synthetic potential. However, their chemical reactivity remains unexplored owing mainly to the lack of synthetic accessibility. We report herein a versatile copper-catalyzed synthesis of ynimines from readily available O-acetyl ketoximes and terminal alkynes. A wide range of O-acetyl ketoximes derived from diaryl ketones, aryl alkyl ketones and dialkyl ketones underwent cross-coupling with a diverse set of terminal alkynes to afford the ynimines in good to excellent yields. An unprecedented [5+1] heteroannulation reaction exploiting the reactivity of the ynimine generated in situ was subsequently developed for the synthesis of medicinally important heterocycles, including isoquinolines, azaindoles, azabenzofurans, azabenzothiophenes and carbolines.

N6-SUBSTITUTED ADENOSINE DERIVATIVES AND N6-SUBSTITUTED ADENINE DERIVATIVES AND USES THEREOF

The present invention provides N6-substituted adenosine derivatives and N6-substituted adenine derivatives, manufacturing methods thereof, a pharmaceutical composition comprising the said compounds above, and uses of these compounds in manufacturing medicaments and health-care products for treating insomnia, convulsion, epilepsy, and Parkinson's diseases, and preventing and treating dementia.