5421-40-9

Basic information

• Product Name: 4'-methoxybutyranilide
• Synonyms: 4'-methoxybutyranilide;N-(4-Methoxyphenyl)butanamide
• CAS NO: 5421-40-9
• Molecular Formula: C₁₁H₁₅NO₂
• Molecular Weight: 193.2423
• EINECS: 226-539-3
• Mol File: 5421-40-9.mol
• Article Data: 22

Chemical Properties

• Boiling Point: 365.8°Cat760mmHg
• Flash Point: 175°C
• Appearance: /
• Density: 1.076g/cm³
• CAS DataBase Reference: 4'-methoxybutyranilide(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-methoxybutyranilide(5421-40-9)
• EPA Substance Registry System: 4'-methoxybutyranilide(5421-40-9)

Safety Data

• Hazardous Substances Data: 5421-40-9(Hazardous Substances Data)

Usage

General Description

4'-methoxybutyranilide, also known as 4-methoxy-N-butylacetanilide, is a chemical compound that is commonly used as a fragrance ingredient in cosmetics and personal care products. It belongs to the class of compounds known as acetanilides, which are organic compounds containing an acetamide group conjugated to a phenyl group. 4'-methoxybutyranilide has a slightly sweet, floral scent and is often used in perfumes, lotions, and other scented products. In addition to its use in the fragrance industry, it has also been studied for its potential antimicrobial and anti-inflammatory properties. However, it is important to note that there may be concerns over potential health risks and allergic reactions associated with exposure to this chemical, and it is important to use it cautiously and in accordance with safety guidelines. Overall, 4'-methoxybutyranilide is a versatile compound with applications in both the fragrance and pharmaceutical industries.

Upstream product

• 627-05-4 1-nitrobutane 
• 100-66-3 methoxybenzene 
• 623-42-7 butanoic acid methyl ester 
• 104-94-9 4-methoxy-aniline 
• 693-03-8 n-butyl magnesium bromide 
• 332-34-3 2,2,2-trifluoro-N-(4-methoxy-phenyl)-acetamide 
• 541-35-5 butanamide 
• 423115-90-6 1-(4-methoxyphenyl)butanone oxime 
• 100-17-4 para-methoxynitrobenzene 
• 107-92-6 butyric acid 
• 141-75-3 butyryl chloride 
• 696-62-8 para-iodoanisole 
• 61829-43-4 N-butyl-4-methoxyaniline 
• 783-08-4 [4-(benzylideneamino)phenyl]methanol 

Downstream Products

• 35274-21-6 N-(4-methoxyphenyl)butanethioamide 
• 122846-18-8 N-<(tert-butoxycarbonyl)methyl>-N-(4-methoxyphenyl)butanamide 
• 117901-09-4 cis-4-(tert-butoxycarbonyl)-3-ethyl-1-(4-methoxyphenyl)-2-azetidinone 
• 137242-86-5 trans-1-(4-methoxyphenyl)-3-phthalimido-4-(n-propyl)-4-methylthio-azetidin-2-one 
• 137242-85-4 trans-1-(4-methoxyphenyl)-3-phenoxy-4-(n-propyl)-4-methylthio-azetidin-2-one 
• 137242-80-9 S-methyl N-(4-methoxyphenyl)-butanethioimidate 

Relevant articles and documents

Organocatalytic and enantioselective [4+2] cyclization between hydroxymaleimides and: Ortho -hydroxyphenyl para -quinone methide-selective preparation of chiral hemiketals

A cinchona alkaloid squaramide promoted enantioselective [4+2] cyclization between hydroxymaleimides and ortho-hydroxyphenyl p-QMs has been disclosed, and a wide range of chiral hemiketals containing chromane and succinimide frameworks with two adjacent quaternary stereogenic centers have been prepared for the first time with excellent results (up to 99% yield, up to 99?:?1 dr, up to >99% ee) under mild conditions. This journal is

A non-catalyst non-promoter under the conditions of amide derivatives of aromatic amine with transfers the amine reaction

The present invention discloses a non-catalyst under the condition of non-accelerator [...] amide derivatives of aromatic amine with transfers the amine reaction, yield of synthetic N - aryl amide derivatives. The method has a wide range of the substrate, its raw materials and cheap and easy to obtain acylation reagent, the reaction yield is high, one-step reaction, low cost, high reaction selectivity, simple operation and the like. Adopting this method can be gram scale can realize the high yield of the synthesis of drug molecules. Therefore, the method in the N - aryl amide derivatives of synthesis application field has very good application prospect. The method overcomes the existing technologies such as the reaction reagent toxicity is large, the need to use different type catalyst, synthesis method and the cost is high, more reaction steps, more byproducts and the like.

Preparation method of amide compounds

The invention discloses a novel preparation method of amide compounds. According to the preparation method, perfluoroalkyl amide is taken as the raw material, a transition metal catalyst is adopted, perfluoroalkyl amide carries out reactions for a while in an organic aprotic solvent at a certain temperature, amide compounds can be obtained high selectively, and the yield is high. The preparation method has the advantages of low cost, high yield, and simple and convenient operation, and can be possibly applied to industrial production.