423166-75-0

Basic information

• Product Name: Acetic acid 4-[(E)-1-(4'-bromo-biphenyl-4-yl)-3-dimethylamino-propenyl]-phenyl ester
• Synonyms: Acetic acid 4-[(E)-1-(4'-bromo-biphenyl-4-yl)-3-dimethylamino-propenyl]-phenyl ester
• CAS NO: 423166-75-0
• Molecular Weight: 450.375
• Mol File: 423166-75-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Acetic acid 4-[(E)-1-(4'-bromo-biphenyl-4-yl)-3-dimethylamino-propenyl]-phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid 4-[(E)-1-(4'-bromo-biphenyl-4-yl)-3-dimethylamino-propenyl]-phenyl ester(423166-75-0)
• EPA Substance Registry System: Acetic acid 4-[(E)-1-(4'-bromo-biphenyl-4-yl)-3-dimethylamino-propenyl]-phenyl ester(423166-75-0)

Safety Data

• Hazardous Substances Data: 423166-75-0(Hazardous Substances Data)

Upstream product

• 92-66-0 4-bromo-1,1'-biphenyl 
• 21331-80-6 [2-(dimethylamino)ethyl]triphenylphosphonium bromide 
• 259268-32-1 acetic acid 4-(4'-bromo-biphenyl-4-carbonyl)-phenyl ester 
• 27914-73-4 4-acetoxybenzoyl chloride 

Relevant articles and documents

Synthesis, antimycobacterial activities and cytotoxicity on V79 of 3-[4′-Y-(1,1′-biphenyl)-4-yl]-N,N-dimethyl-3-(4-X-phenyl)-2- propen-1-amine derivatives

The derivatives of 3-(4′-bromo-[1,1′-biphenyl]-4-yl)-3-(4-X-phenyl)-N,N-dimethyl-2- propen-1-amine (5a-m) were synthesised through a Friedel-Crafts acylation followed by Wittig reaction. The effects of the compounds on standard strains of Mycobacterium sp. (ATCC) and M. tuberculosis isolated from clinical specimens were evaluated. Also the toxicity was determined on V79 cells line using neutral red uptake (NRU), nucleic acid content (NAC) and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction to measure the cellular viability.