4233-58-3

Usage

Uses

Used in Flavor and Fragrance Industry:
6-Oxooctanoic acid ethyl ester is used as a flavoring agent for its fruity and apple-like aroma, enhancing the taste and scent of various products in the flavor and fragrance industry.
Used in Food and Beverage Industry:
In the food and beverage industry, 6-Oxooctanoic acid ethyl ester is used as a flavor enhancer to improve the taste and aroma of different food products and beverages, providing a pleasant and appealing sensory experience for consumers.
Used in Pharmaceutical Synthesis:
6-Oxooctanoic acid ethyl ester is utilized in the synthesis of pharmaceuticals and other organic compounds, contributing to the development of new drugs and medicinal products.

InChI:InChI=1/C10H18O3/c1-3-9(11)7-5-6-8-10(12)13-4-2/h3-8H2,1-2H3

Upstream product

• 141-28-6 diethyl adipate 
• 1071-71-2 ethyl 6-chloro-6-oxohexanoate 
• 592-02-9 diethylcadmium 
• 64-17-5 ethanol 
• 4423-94-3 2-ethylcyclohexanone 
• 96-22-0 pentan-3-one 
• 140-88-5 ethyl acrylate 
• 14660-52-7 ethyl 5-bromovalerate 

Downstream Products

• 4066-76-6 1,6-octandiol 

Relevant academic research and scientific papers

Iron-Catalyzed C(sp 3)-H Alkylation through Ligand-to-Metal Charge Transfer

We report the FeCl 3-catalyzed alkylation of nonactivated C(sp 3)-H bonds. Photoinduced ligand-to-metal charge transfer at the iron center generates chlorine radicals that then preferentially abstract hydrogen atoms from electron-ric

Efficient Synthesis of Polysubstituted 1,5-Benzodiazepinone Dipeptide Mimetics via an Ugi-4CR-Ullmann Condensation Sequence

An efficient three-step synthesis towards 3-amino-1,4-benzodiazepin-2-one derivatives is presented. The versatile Ugi-4-component reaction (Ugi-4CR) and Boc deprotection is followed by a ligand-free Ullmann condensation. This protocol allows the rapid construction of a diverse array of substituted 1,5-benzodiazepinones. Since Ugi-based products are typically limited by their 'inert' C -terminal amides, the use of a convertible ('cleavable') isocyanide was envisaged and resulted in building blocks that can be made SPPS compatible. To demonstrate the potential of this novel synthetic route, the design and preparation of novel phenylurea-1,5-benzodiazepin-4(5 H)-one dipeptide mimetics with potential CCK2-antagonist properties is reported.

Synthesis of Diketones, Ketoesters, and Tetraketones by Electrochemical Oxidative Decarboxylation of Malonic Acid Derivatives: Application to the Synthesis of cis-Jasmone

Disubstituted malonic acid derivatives are smoothly converted into diketones and ketoesters in good to excellent yield (68% to 91%) under electrochemical conditions. The scope can be extended to transform trisubstituted bis-malonic acids into tetraketones in 77% to 86% yield. The new method was applied to the total synthesis of cis-jasmone.

Synthesis of Diketones, Ketoesters, and Tetraketones by Electrochemical Oxidative Decarboxylation of Malonic Acid Derivatives: Application to the Synthesis of cis-Jasmone

Disubstituted malonic acid derivatives are smoothly converted into diketones and ketoesters in good to excellent yield (68% to 91%) under electrochemical conditions. The scope can be extended to transform trisubstituted bis-malonic acids into tetraketones in 77% to 86% yield. The new method was applied to the total synthesis of cis-jasmone.

Oxidation of 2-substituted cycloalkanones with cerium(IV) sulfate tetrahydrate in alcohols and acetic acid

The reaction of 2-substituted cycloalkanones with cerium(IV) sulfate tetrahydrate (CS) in alcohols and acetic acid gave the corresponding alkyl esters of oxo acids (80-96%) and oxo acids (78-96%), respectively, by oxidative cleavage of the C(R).C=O bond. In the case of 2-iodocycloalkanones in methanol, the dimethyl ester was obtained in good yield. A treatment of 5α-cholestan-3-one with CS in methanol produced 2-acetal 3-ester of 2,3-seco derivative in good yield. The effects of cerium(IV) and copper(II) salts are also discussed.