42365-73-1

Usage

Uses

Used in Pharmaceutical Industry:
4-(4-Fluorophenyl)-1,3-thiazole-2-thiol is utilized as a key component in drug design and development due to its potential biological activity. It serves as a building block for creating new antimicrobial, antifungal, and antiviral agents, contributing to the fight against various infectious diseases.
Used in Agrochemical Industry:
In the agrochemical sector, 4-(4-Fluorophenyl)-1,3-thiazole-2-thiol is employed for its potential to develop new compounds with pesticidal properties, aiming to enhance crop protection and yield.
Used in Materials Science:
4-(4-Fluorophenyl)-1,3-thiazole-2-thiol is used as a component in the development of organic electronic devices, leveraging its unique structural properties to improve device performance and functionality.
Used as an Antioxidant:
4-(4-Fluorophenyl)-1,3-thiazole-2-thiol is also studied for its potential as an antioxidant, which could have applications in various industries, including food preservation, cosmetics, and pharmaceuticals, to prevent oxidative damage and extend shelf life.
Further research and studies are ongoing to explore the diverse potential applications of 4-(4-Fluorophenyl)-1,3-thiazole-2-thiol across different fields, highlighting its versatility and importance in modern scientific and industrial applications.

InChI:InChI=1/C9H6FNS2/c10-7-3-1-6(2-4-7)8-5-13-9(12)11-8/h1-5H,(H,11,12)

Upstream product

• 513-74-6 ammonium dithiocarbamate 
• 357952-79-5 1-(4-fluorophenyl)-2-(p-tolylsulfonyloxy)ethanone 
• 403-29-2 2-bromo-4'-fluoroacetophenone 

Downstream Products

• 3827-55-2 4-(4-fluoro-phenyl)-2-(2-nitro-phenyldisulfanyl)-thiazole 
• 1555-32-4 2-(4-chloro-phenyldisulfanyl)-4-(4-fluoro-phenyl)-thiazole 
• 1493-44-3 4-(4-fluoro-phenyl)-2-phenyldisulfanyl-thiazole 
• 1537-09-3 2-(2,4-dinitro-phenyldisulfanyl)-4-(4-fluoro-phenyl)-thiazole 
• 1537-18-4 2-(2-chloro-phenyldisulfanyl)-4-(4-fluoro-phenyl)-thiazole 
• 1493-77-2 2-(4-chloro-2-nitro-phenyldisulfanyl)-4-(4-fluoro-phenyl)-thiazole 
• 1583-53-5 4-(4-fluoro-phenyl)-2-p-tolyldisulfanyl-thiazole 

Relevant academic research and scientific papers

Synthesis of novel azabicyclo derivatives containing a thiazole moiety and their biological activity against pine-wood nematodes

To explore a new skeleton with nematicidal activity, a series of novel azabicyclo derivatives containing a thiazole moiety were designed, synthesized and evaluated for their nematicidal activities. The bioassay results against pine-wood nematodes (Bursaphelenchus xylophilus) showed that most of the title compounds displayed nematicidal activity at a concentration of 40 mg/L. Especially, the title compounds2-((8-methyl-8-azabicyclo[3.2.1]octan-3-yl)oxy)-4-(4-chlorophenyl)thiazole (7e), 2-((8-methyl-8-azabicyclo[3.2.1]octan-3-yl)thio)-4-phenylthiazole (10a) and 2-((8-methyl-8-azabicyclo [3.2.1]octan-3-yl)thio)-4-(4-chlorophenyl)thiazole (10e) exhibited more than 90% mortality against Bursaphelenchus xylophilus.

Hypervalent iodine in synthesis; 60: A novel method for the synthesis of 2-mercaptothiazoles by cyclocondensation of alkynyl(phenyl)iodonium salts and ammonium dithiocarbamate

A novel method for the synthesis of 2-mercaptothiazoles is achieved by cyclocondensation of alkynyl(phenyl)iodonium salts with ammonium dithiocarbamate. A reaction mechanism is proposed.

Hypervalent iodine in synthesis. 48. A one-pot convenient procedure for the synthesis of 2-mercaptothiazoles by cyclocondensation of ketones with [hydroxy(tosyloxy)iodo]-benzene and ammonium dithiocarbamate

α-Tosyloxylation of ketones with [hydroxy(tosyloxy)iodo]-benzene (HTIB), followed by treatment with ammonium dithiocarbamate, provides a one-pot convenient procedure for the synthesis of 2-mercaptothiazoles with good yields.