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(1-Methanesulfonyl-piperidin-4-yl)-acetic acid, also known as MSPA, is a chemical compound that serves as a building block in the pharmaceutical industry for the synthesis of various drugs. It features a piperidine ring with a methanesulfonyl group attached and an acetic acid moiety. The methanesulfonyl group acts as a protecting group for amines in organic synthesis, while the piperidine ring is a prevalent scaffold in many biologically active compounds. The acetic acid component of the molecule allows for additional chemical modifications, making MSPA crucial for the development of new drugs with potential therapeutic applications.

423722-27-4

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423722-27-4 Usage

Uses

Used in Pharmaceutical Industry:
(1-Methanesulfonyl-piperidin-4-yl)-acetic acid is used as a building block for the synthesis of various drugs due to its versatile chemical structure and the presence of a piperidine ring, which is a common scaffold in many biologically active compounds.
Used in Organic Synthesis:
(1-Methanesulfonyl-piperidin-4-yl)-acetic acid is used as a protecting group for amines, particularly in the synthesis of complex organic molecules where the protection of amine groups is necessary to prevent unwanted side reactions.
Used in Drug Development:
(1-Methanesulfonyl-piperidin-4-yl)-acetic acid is used as a starting material for the development of new drugs with potential therapeutic applications, thanks to its ability to be chemically modified and its presence in biologically active compounds.

Check Digit Verification of cas no

The CAS Registry Mumber 423722-27-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,2,3,7,2 and 2 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 423722-27:
(8*4)+(7*2)+(6*3)+(5*7)+(4*2)+(3*2)+(2*2)+(1*7)=124
124 % 10 = 4
So 423722-27-4 is a valid CAS Registry Number.

423722-27-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name (1-methanesulfonyl-piperidin-4-yl)-acetic acid

1.2 Other means of identification

Product number -
Other names [1-(methylsulphonyl)piperidin-4-yl]acetic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:423722-27-4 SDS

423722-27-4Downstream Products

423722-27-4Relevant academic research and scientific papers

BENZIMIDAZOLE DERIVATIVES AS MODULATORS OF ROR-GAMMA

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Paragraph 00181-00182, (2017/08/21)

Provided are novel compounds of Formula I: pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of diseases and disorders mediated by RORy. Also provided are pharmaceutical compositions comprising the novel compounds of Formula I and methods for their use in treating one or more inflammatory, metabolic, autoimmune and other diseases or disorders.

USE OF PIPERIDINE DERIVATIVES AS AGONISTS OF CHEMOKINE RECEPTOR ACTIVITY

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Page/Page column 90, (2009/03/07)

The present invention is directed to novel piperidinc derivatives and to the use of piperidine derivatives of formula (I) as agonists of chemokine receptor activity.

USE OF COMPOUNDS HAVING CCR ANTAGONISM

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Page/Page column 85, (2010/02/10)

It is intended to provide preventives/remedies for graft-versus-host disease and/or rejection in organ or bone marrow transplantation, rheumatoid arthritis, autoimmune diseases, allergic diseases, ischemic cerebral cell injury, myocardial infarction, chro

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