4238-57-7 Usage
General Description
N^2^-formylglycinamide, also known as 2-Formylglycinamide or N^2^-Formylglycine amide, is a chemical compound with the molecular formula C3H6N2O2. It is an intermediate in the metabolism of purine nucleotides and is involved in the biosynthesis of purine nucleotides. N^2^-formylglycinamide is a key intermediate in the conversion of glycinamide ribonucleotide to formylglycinamide ribonucleotide, which is an important step in the de novo synthesis of purine nucleotides. N~2~-formylglycinamide has been studied for its potential therapeutic applications in the treatment of cancer and other diseases related to purine metabolism.
Check Digit Verification of cas no
The CAS Registry Mumber 4238-57-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,2,3 and 8 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 4238-57:
(6*4)+(5*2)+(4*3)+(3*8)+(2*5)+(1*7)=87
87 % 10 = 7
So 4238-57-7 is a valid CAS Registry Number.
4238-57-7Relevant articles and documents
Neighbouring Group Participation of the N-Acyl Function. I: A Selective Conversion of Nitriles into Carboxamides by Formic Acid
Friedrich, Klaus,Zamkanei, Mohebullah,Zimmer, Ralph
, p. 404 - 408 (2007/10/03)
Aliphatic α-(acylamino)nitriles react with formic acid at room temperature to give the corresponding α-(acyl-amino)carboxamides with concomitant formation of one mole of carbon monoxide. This new reaction, which was first observed with 2-acylamino-2-cyano-3,6-dihydro-2H-thiapyranes 1, can also be used to convert other N-(α-cyanoalkyl) amides such as N-cyanomethylbenzamides 3, 5 and the 3,4-dihydro Reissert compound 16 into the corresponding carboxamides. Another application is a synthesis of 2-formylaminoacetamides 11. A mechanism for the reaction is proposed.
